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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3r8zZ63Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3r8zZ63Cyclin-dependent kinase 22.7.11.221.000
3qxpX64Cyclin-dependent kinase 22.7.11.220.594
3rkb12ZCyclin-dependent kinase 22.7.11.220.587
3r9dX6BCyclin-dependent kinase 22.7.11.220.580
4erwSTUCyclin-dependent kinase 22.7.11.220.575
1gih1PUCyclin-dependent kinase 22.7.11.220.567
2bheBRYCyclin-dependent kinase 22.7.11.220.563
2w05FRTCyclin-dependent kinase 22.7.11.220.559
2fvdLIACyclin-dependent kinase 22.7.11.220.556
3qwjX6ACyclin-dependent kinase 22.7.11.220.555
1v1k3FPCyclin-dependent kinase 22.7.11.220.548
2j9mPY8Cyclin-dependent kinase 22.7.11.220.543
3lfsA07Cyclin-dependent kinase 22.7.11.220.535
3r7iX9ICyclin-dependent kinase 22.7.11.220.533
1oiqHDUCyclin-dependent kinase 22.7.11.220.530
3uli1N3Cyclin-dependent kinase 22.7.11.220.528
3qtqX35Cyclin-dependent kinase 22.7.11.220.525
2uznC96Cyclin-dependent kinase 22.7.11.220.524
2r64740Cyclin-dependent kinase 22.7.11.220.506
1aq1STUCyclin-dependent kinase 22.7.11.220.505
4fkw62KCyclin-dependent kinase 22.7.11.220.496
2w1hL0FCyclin-dependent kinase 22.7.11.220.495
3rmf20ZCyclin-dependent kinase 22.7.11.220.494
3ral04ZCyclin-dependent kinase 22.7.11.220.493
4ez30S0Cyclin-dependent kinase 22.7.11.220.491
3le62BZCyclin-dependent kinase 22.7.11.220.488
3rk708ZCyclin-dependent kinase 22.7.11.220.488
3qtzX42Cyclin-dependent kinase 22.7.11.220.486
3tnwF18Cyclin-dependent kinase 22.7.11.220.483
3lfqA28Cyclin-dependent kinase 22.7.11.220.477
3r9hZ67Cyclin-dependent kinase 22.7.11.220.477
4nj32KDCyclin-dependent kinase 22.7.11.220.473
4ez50RSCyclin-dependent kinase 62.7.11.220.472
2vu3LZECyclin-dependent kinase 22.7.11.220.471
3rak03ZCyclin-dependent kinase 22.7.11.220.469
3rk507ZCyclin-dependent kinase 22.7.11.220.469
3rni21ZCyclin-dependent kinase 22.7.11.220.468
3s1h56ZCyclin-dependent kinase 22.7.11.220.468
2r3lSCWCyclin-dependent kinase 22.7.11.220.465
2r3p3SCCyclin-dependent kinase 22.7.11.220.462
3qtxX43Cyclin-dependent kinase 22.7.11.220.462
3qzfX66Cyclin-dependent kinase 22.7.11.220.462
3py0SU9Cyclin-dependent kinase 22.7.11.220.460
3r1qX75Cyclin-dependent kinase 22.7.11.220.460
3rpv26ZCyclin-dependent kinase 22.7.11.220.459
4fko20KCyclin-dependent kinase 22.7.11.220.458
1w0xOLOCyclin-dependent kinase 22.7.11.220.455
1pkdUCNCyclin-dependent kinase 22.7.11.220.454
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.454
3nup3NUCyclin-dependent kinase 62.7.11.220.454
2iw84SPCyclin-dependent kinase 22.7.11.220.453
3qziX72Cyclin-dependent kinase 22.7.11.220.453
1ke9LS5Cyclin-dependent kinase 22.7.11.220.452
3ig7EFPCyclin-dependent kinase 22.7.11.220.452
4fx360KCyclin-dependent kinase 22.7.11.220.452
1fvt106Cyclin-dependent kinase 22.7.11.220.451
2vtrLZBCyclin-dependent kinase 22.7.11.220.451
2w06FRVCyclin-dependent kinase 22.7.11.220.451
3dogNNNCyclin-dependent kinase 22.7.11.220.451
4fki09KCyclin-dependent kinase 22.7.11.220.450
1oiyN41Cyclin-dependent kinase 22.7.11.220.448
1p2a5BNCyclin-dependent kinase 22.7.11.220.448
4ek610KCyclin-dependent kinase 22.7.11.220.448
1g5sI17Cyclin-dependent kinase 22.7.11.220.447
3qtrX36Cyclin-dependent kinase 22.7.11.220.447
3qwkX62Cyclin-dependent kinase 22.7.11.220.447
4acm7YGCyclin-dependent kinase 22.7.11.220.447
3fz1B98Cyclin-dependent kinase 22.7.11.220.446
3roy22ZCyclin-dependent kinase 22.7.11.220.446
1ke6LS2Cyclin-dependent kinase 22.7.11.220.445
1pyePM1Cyclin-dependent kinase 22.7.11.220.445
1urwI1PCyclin-dependent kinase 22.7.11.220.445
2c6tDT5Cyclin-dependent kinase 22.7.11.220.445
3qtwX3ACyclin-dependent kinase 22.7.11.220.445
2i40BLZCyclin-dependent kinase 22.7.11.220.444
4fkr45KCyclin-dependent kinase 22.7.11.220.444
2wihP48Cyclin-dependent kinase 22.7.11.220.443
3ddpRC8Cyclin-dependent kinase 22.7.11.220.443
3qqkX02Cyclin-dependent kinase 22.7.11.220.443
3sw719KCyclin-dependent kinase 22.7.11.220.443
4fkt48KCyclin-dependent kinase 22.7.11.220.443
2cchATPCyclin-dependent kinase 22.7.11.220.442
2ds11CDCyclin-dependent kinase 22.7.11.220.442
2duv371Cyclin-dependent kinase 22.7.11.220.442
1h1s4SPCyclin-dependent kinase 22.7.11.220.441
3rjc06ZCyclin-dependent kinase 22.7.11.220.441
2xmyCDKCyclin-dependent kinase 22.7.11.220.440
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440