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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3fz1B98Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3fz1B98Cyclin-dependent kinase 22.7.11.221.000
2r3jSCJCyclin-dependent kinase 22.7.11.220.546
3r1yX76Cyclin-dependent kinase 22.7.11.220.541
4nj32KDCyclin-dependent kinase 22.7.11.220.538
3r7yZ04Cyclin-dependent kinase 22.7.11.220.528
2r3p3SCCyclin-dependent kinase 22.7.11.220.524
1pxmCK5Cyclin-dependent kinase 22.7.11.220.521
2c6o4SPCyclin-dependent kinase 22.7.11.220.518
4ek610KCyclin-dependent kinase 22.7.11.220.516
2fvdLIACyclin-dependent kinase 22.7.11.220.510
4fkq42KCyclin-dependent kinase 22.7.11.220.509
4fkt48KCyclin-dependent kinase 22.7.11.220.509
2r3mSCXCyclin-dependent kinase 22.7.11.220.505
3r7vZ02Cyclin-dependent kinase 22.7.11.220.505
3pxyJWSCyclin-dependent kinase 22.7.11.220.504
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.502
3lfnA27Cyclin-dependent kinase 22.7.11.220.502
3rpv26ZCyclin-dependent kinase 22.7.11.220.502
2j9mPY8Cyclin-dependent kinase 22.7.11.220.501
2r3iSCFCyclin-dependent kinase 22.7.11.220.501
3lfqA28Cyclin-dependent kinase 22.7.11.220.501
3rm719ZCyclin-dependent kinase 22.7.11.220.501
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.500
3s1h56ZCyclin-dependent kinase 22.7.11.220.500
3r8lZ30Cyclin-dependent kinase 22.7.11.220.498
1y91CT9Cyclin-dependent kinase 22.7.11.220.494
2a0cCK9Cyclin-dependent kinase 22.7.11.220.491
4fklCK2Cyclin-dependent kinase 22.7.11.220.491
2vv9IM9Cyclin-dependent kinase 22.7.11.220.490
3wblPDYCyclin-dependent kinase 22.7.11.220.490
4fki09KCyclin-dependent kinase 22.7.11.220.490
1ykr628Cyclin-dependent kinase 22.7.11.220.489
2r3lSCWCyclin-dependent kinase 22.7.11.220.489
2c6lDT4Cyclin-dependent kinase 22.7.11.220.488
3r7uX96Cyclin-dependent kinase 22.7.11.220.487
1w0xOLOCyclin-dependent kinase 22.7.11.220.486
1ke5LS1Cyclin-dependent kinase 22.7.11.220.483
3lfsA07Cyclin-dependent kinase 22.7.11.220.483
2btrU73Cyclin-dependent kinase 22.7.11.220.482
2vthLZ2Cyclin-dependent kinase 22.7.11.220.482
3qzgX67Cyclin-dependent kinase 22.7.11.220.482
4fkr45KCyclin-dependent kinase 22.7.11.220.482
1ke6LS2Cyclin-dependent kinase 22.7.11.220.481
2xmyCDKCyclin-dependent kinase 22.7.11.220.481
3rk507ZCyclin-dependent kinase 22.7.11.220.481
3rni21ZCyclin-dependent kinase 22.7.11.220.481
1oitHDTCyclin-dependent kinase 22.7.11.220.480
1pxoCK7Cyclin-dependent kinase 22.7.11.220.480
3ezvEZVCyclin-dependent kinase 22.7.11.220.480
3qxpX64Cyclin-dependent kinase 22.7.11.220.477
1pxpCK8Cyclin-dependent kinase 22.7.11.220.476
3iggEFQCyclin-dependent kinase 22.7.11.220.476
3qwjX6ACyclin-dependent kinase 22.7.11.220.476
2btsU32Cyclin-dependent kinase 22.7.11.220.473
3r7iX9ICyclin-dependent kinase 22.7.11.220.473
3rak03ZCyclin-dependent kinase 22.7.11.220.473
1g5sI17Cyclin-dependent kinase 22.7.11.220.472
3qqfX07Cyclin-dependent kinase 22.7.11.220.472
3sw719KCyclin-dependent kinase 22.7.11.220.472
4acm7YGCyclin-dependent kinase 22.7.11.220.472
2uzoC62Cyclin-dependent kinase 22.7.11.220.471
1ke7LS3Cyclin-dependent kinase 22.7.11.220.470
1p2a5BNCyclin-dependent kinase 22.7.11.220.470
3sw418KCyclin-dependent kinase 22.7.11.220.470
3r9nZ68Cyclin-dependent kinase 22.7.11.220.469
1gii1PUCyclin-dependent kinase 22.7.11.220.468
3rkb12ZCyclin-dependent kinase 22.7.11.220.468
4ek816KCyclin-dependent kinase 22.7.11.220.468
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.467
2a4lRRCCyclin-dependent kinase 22.7.11.220.466
4fkpLS5Cyclin-dependent kinase 22.7.11.220.465
3raiX85Cyclin-dependent kinase 22.7.11.220.464
3rk708ZCyclin-dependent kinase 22.7.11.220.463
3roy22ZCyclin-dependent kinase 22.7.11.220.462
2vu3LZECyclin-dependent kinase 22.7.11.220.461
1pxkCK3Cyclin-dependent kinase 22.7.11.220.459
2b53D23Cyclin-dependent kinase 22.7.11.220.459
2w17I19Cyclin-dependent kinase 22.7.11.220.459
3r9hZ67Cyclin-dependent kinase 22.7.11.220.459
3qu0X40Cyclin-dependent kinase 22.7.11.220.458
3rm618ZCyclin-dependent kinase 22.7.11.220.458
1h1s4SPCyclin-dependent kinase 22.7.11.220.457
1w8cN69Cyclin-dependent kinase 22.7.11.220.457
2c6iDT1Cyclin-dependent kinase 22.7.11.220.457
3qqlX03Cyclin-dependent kinase 22.7.11.220.457
2b52D42Cyclin-dependent kinase 22.7.11.220.456
4fko20KCyclin-dependent kinase 22.7.11.220.456
2r3kSCQCyclin-dependent kinase 22.7.11.220.455
3le62BZCyclin-dependent kinase 22.7.11.220.455
3rahO1ZCyclin-dependent kinase 22.7.11.220.455
1gih1PUCyclin-dependent kinase 22.7.11.220.454
2uznC96Cyclin-dependent kinase 22.7.11.220.454
3qtsX46Cyclin-dependent kinase 22.7.11.220.454
4fkj11KCyclin-dependent kinase 22.7.11.220.454
2w05FRTCyclin-dependent kinase 22.7.11.220.453
3r7eX88Cyclin-dependent kinase 22.7.11.220.453
3qqhX0ACyclin-dependent kinase 22.7.11.220.452
3qtxX43Cyclin-dependent kinase 22.7.11.220.452
3pj8404Cyclin-dependent kinase 22.7.11.220.451
3rjc06ZCyclin-dependent kinase 22.7.11.220.451
1dm2HMDCyclin-dependent kinase 22.7.11.220.450
2r3r6SCCyclin-dependent kinase 22.7.11.220.450
3uli1N3Cyclin-dependent kinase 22.7.11.220.450
4bgh3I6Cyclin-dependent kinase 22.7.11.220.450
1oirHDYCyclin-dependent kinase 22.7.11.220.449
3qtuX44Cyclin-dependent kinase 22.7.11.220.449
2x1nX1NCyclin-dependent kinase 22.7.11.220.448
3r73X87Cyclin-dependent kinase 22.7.11.220.448
3ezrEZRCyclin-dependent kinase 22.7.11.220.446
3rpy27ZCyclin-dependent kinase 22.7.11.220.446
1pxlCK4Cyclin-dependent kinase 22.7.11.220.444
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.444
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.444
3qxoX65Cyclin-dependent kinase 22.7.11.220.444
1h1r6CPCyclin-dependent kinase 22.7.11.220.443
3qziX72Cyclin-dependent kinase 22.7.11.220.443
4erwSTUCyclin-dependent kinase 22.7.11.220.443
3ddqRRCCyclin-dependent kinase 22.7.11.220.442
3qzhX69Cyclin-dependent kinase 22.7.11.220.442
3s2pPMUCyclin-dependent kinase 22.7.11.220.442
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.441
3qx2X63Cyclin-dependent kinase 22.7.11.220.441
3r83Z14Cyclin-dependent kinase 22.7.11.220.441
4lyn1YGCyclin-dependent kinase 22.7.11.220.441
3qtrX36Cyclin-dependent kinase 22.7.11.220.440
3ral04ZCyclin-dependent kinase 22.7.11.220.440
4fks46KCyclin-dependent kinase 22.7.11.220.440