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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vthLZ2Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2vthLZ2Cyclin-dependent kinase 22.7.11.221.000
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.612
4ek610KCyclin-dependent kinase 22.7.11.220.595
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.593
2c6o4SPCyclin-dependent kinase 22.7.11.220.562
1oitHDTCyclin-dependent kinase 22.7.11.220.560
1ke5LS1Cyclin-dependent kinase 22.7.11.220.551
1pxmCK5Cyclin-dependent kinase 22.7.11.220.551
4fkt48KCyclin-dependent kinase 22.7.11.220.549
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.543
1p2a5BNCyclin-dependent kinase 22.7.11.220.539
1gii1PUCyclin-dependent kinase 22.7.11.220.536
4fkpLS5Cyclin-dependent kinase 22.7.11.220.534
4fkq42KCyclin-dependent kinase 22.7.11.220.533
2btrU73Cyclin-dependent kinase 22.7.11.220.532
3lfnA27Cyclin-dependent kinase 22.7.11.220.532
1ykr628Cyclin-dependent kinase 22.7.11.220.531
2r3lSCWCyclin-dependent kinase 22.7.11.220.526
3lfqA28Cyclin-dependent kinase 22.7.11.220.524
3r8lZ30Cyclin-dependent kinase 22.7.11.220.524
4fkg4CKCyclin-dependent kinase 22.7.11.220.522
3qzgX67Cyclin-dependent kinase 22.7.11.220.520
4bgh3I6Cyclin-dependent kinase 22.7.11.220.519
4fki09KCyclin-dependent kinase 22.7.11.220.515
2btsU32Cyclin-dependent kinase 22.7.11.220.514
1gih1PUCyclin-dependent kinase 22.7.11.220.511
3ezvEZVCyclin-dependent kinase 22.7.11.220.510
3s2pPMUCyclin-dependent kinase 22.7.11.220.509
1ke6LS2Cyclin-dependent kinase 22.7.11.220.508
3r7yZ04Cyclin-dependent kinase 22.7.11.220.508
3wblPDYCyclin-dependent kinase 22.7.11.220.508
2vv9IM9Cyclin-dependent kinase 22.7.11.220.507
2w1hL0FCyclin-dependent kinase 22.7.11.220.506
2r3jSCJCyclin-dependent kinase 22.7.11.220.505
3r1yX76Cyclin-dependent kinase 22.7.11.220.505
1oirHDYCyclin-dependent kinase 22.7.11.220.501
1v1k3FPCyclin-dependent kinase 22.7.11.220.498
3iggEFQCyclin-dependent kinase 22.7.11.220.498
3r83Z14Cyclin-dependent kinase 22.7.11.220.497
1w0xOLOCyclin-dependent kinase 22.7.11.220.496
1w8cN69Cyclin-dependent kinase 22.7.11.220.496
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.496
3s1h56ZCyclin-dependent kinase 22.7.11.220.496
1pxoCK7Cyclin-dependent kinase 22.7.11.220.495
2w06FRVCyclin-dependent kinase 22.7.11.220.495
3qxoX65Cyclin-dependent kinase 22.7.11.220.494
2xmyCDKCyclin-dependent kinase 22.7.11.220.492
4fkj11KCyclin-dependent kinase 22.7.11.220.492
3le62BZCyclin-dependent kinase 22.7.11.220.489
3rni21ZCyclin-dependent kinase 22.7.11.220.489
3fz1B98Cyclin-dependent kinase 22.7.11.220.488
3r7uX96Cyclin-dependent kinase 22.7.11.220.487
3rm719ZCyclin-dependent kinase 22.7.11.220.486
3sw719KCyclin-dependent kinase 22.7.11.220.486
2vtsLZCCyclin-dependent kinase 22.7.11.220.485
3rk708ZCyclin-dependent kinase 22.7.11.220.484
1pxpCK8Cyclin-dependent kinase 22.7.11.220.483
2uzoC62Cyclin-dependent kinase 22.7.11.220.483
3rkb12ZCyclin-dependent kinase 22.7.11.220.482
2r3kSCQCyclin-dependent kinase 22.7.11.220.481
1pxlCK4Cyclin-dependent kinase 22.7.11.220.479
2w17I19Cyclin-dependent kinase 22.7.11.220.479
3sw418KCyclin-dependent kinase 22.7.11.220.479
3rak03ZCyclin-dependent kinase 22.7.11.220.478
4fks46KCyclin-dependent kinase 22.7.11.220.476
1g5sI17Cyclin-dependent kinase 22.7.11.220.475
3qqlX03Cyclin-dependent kinase 22.7.11.220.475
4ek816KCyclin-dependent kinase 22.7.11.220.474
1di8DTQCyclin-dependent kinase 22.7.11.220.473
3qxpX64Cyclin-dependent kinase 22.7.11.220.473
3lfsA07Cyclin-dependent kinase 22.7.11.220.472
4kd11QKCyclin-dependent kinase 22.7.11.220.472
3qwjX6ACyclin-dependent kinase 22.7.11.220.471
3qqfX07Cyclin-dependent kinase 22.7.11.220.469
4fkv61KCyclin-dependent kinase 22.7.11.220.469
2a4lRRCCyclin-dependent kinase 22.7.11.220.468
2r3iSCFCyclin-dependent kinase 22.7.11.220.468
3rjc06ZCyclin-dependent kinase 22.7.11.220.468
3sqq99ZCyclin-dependent kinase 22.7.11.220.468
1y8yCT7Cyclin-dependent kinase 22.7.11.220.466
1ke7LS3Cyclin-dependent kinase 22.7.11.220.465
3qqkX02Cyclin-dependent kinase 22.7.11.220.465
3r73X87Cyclin-dependent kinase 22.7.11.220.465
3rk909ZCyclin-dependent kinase 22.7.11.220.465
3rmf20ZCyclin-dependent kinase 22.7.11.220.465
2bhhRYUCyclin-dependent kinase 22.7.11.220.464
1y91CT9Cyclin-dependent kinase 22.7.11.220.463
2exmZIPCyclin-dependent kinase 22.7.11.220.463
3rpy27ZCyclin-dependent kinase 22.7.11.220.462
2c6kDT2Cyclin-dependent kinase 22.7.11.220.461
3r8vZ62Cyclin-dependent kinase 22.7.11.220.461
1fvv107Cyclin-dependent kinase 22.7.11.220.460
3raiX85Cyclin-dependent kinase 22.7.11.220.460
1vyzN5BCyclin-dependent kinase 22.7.11.220.459
2r3mSCXCyclin-dependent kinase 22.7.11.220.459
2r3p3SCCyclin-dependent kinase 22.7.11.220.459
2uznC96Cyclin-dependent kinase 22.7.11.220.459
3r1sX73Cyclin-dependent kinase 22.7.11.220.459
4fklCK2Cyclin-dependent kinase 22.7.11.220.459
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.457
3nynSGVG protein-coupled receptor kinase 62.7.11.160.457
3qtuX44Cyclin-dependent kinase 22.7.11.220.456
3qtxX43Cyclin-dependent kinase 22.7.11.220.455
2a0cCK9Cyclin-dependent kinase 22.7.11.220.454
2c69CT8Cyclin-dependent kinase 22.7.11.220.454
3r9hZ67Cyclin-dependent kinase 22.7.11.220.454
4fko20KCyclin-dependent kinase 22.7.11.220.454
3r7vZ02Cyclin-dependent kinase 22.7.11.220.453
2b53D23Cyclin-dependent kinase 22.7.11.220.452
3rahO1ZCyclin-dependent kinase 22.7.11.220.452
1pxkCK3Cyclin-dependent kinase 22.7.11.220.451
3ti1B49Cyclin-dependent kinase 22.7.11.220.451
1h1s4SPCyclin-dependent kinase 22.7.11.220.450
4fkr45KCyclin-dependent kinase 22.7.11.220.450
2c6iDT1Cyclin-dependent kinase 22.7.11.220.449
3rpo24ZCyclin-dependent kinase 22.7.11.220.449
1ckpPVBCyclin-dependent kinase 22.7.11.220.447
3qtzX42Cyclin-dependent kinase 22.7.11.220.447
1dm2HMDCyclin-dependent kinase 22.7.11.220.446
1h0w207Cyclin-dependent kinase 22.7.11.220.446
1oguST8Cyclin-dependent kinase 22.7.11.220.446
2vttLZDCyclin-dependent kinase 22.7.11.220.446
1b38ATPCyclin-dependent kinase 22.7.11.220.445
1pyePM1Cyclin-dependent kinase 22.7.11.220.445
2r3r6SCCyclin-dependent kinase 22.7.11.220.444
3rpv26ZCyclin-dependent kinase 22.7.11.220.443
2bheBRYCyclin-dependent kinase 22.7.11.220.442
4acm7YGCyclin-dependent kinase 22.7.11.220.442
4ez30S0Cyclin-dependent kinase 22.7.11.220.442
2r64740Cyclin-dependent kinase 22.7.11.220.441
3r6xX84Cyclin-dependent kinase 22.7.11.220.441
3r71X86Cyclin-dependent kinase 22.7.11.220.441
3r7iX9ICyclin-dependent kinase 22.7.11.220.441
2j9mPY8Cyclin-dependent kinase 22.7.11.220.440
3r28XA0Cyclin-dependent kinase 22.7.11.220.440