scPDB - Distribution of Cavity Similarity values of 2c6i entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2c6i	DT1	Cyclin-dependent kinase 2	2.7.11.22

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
2c6i	DT1	Cyclin-dependent kinase 2	2.7.11.22	1.000
2r3i	SCF	Cyclin-dependent kinase 2	2.7.11.22	0.632
2r3p	3SC	Cyclin-dependent kinase 2	2.7.11.22	0.596
2r3f	SC8	Cyclin-dependent kinase 2	2.7.11.22	0.556
2btr	U73	Cyclin-dependent kinase 2	2.7.11.22	0.555
4fkt	48K	Cyclin-dependent kinase 2	2.7.11.22	0.551
2r3r	6SC	Cyclin-dependent kinase 2	2.7.11.22	0.550
1w8c	N69	Cyclin-dependent kinase 2	2.7.11.22	0.549
2r3q	5SC	Cyclin-dependent kinase 2	2.7.11.22	0.546
2c6l	DT4	Cyclin-dependent kinase 2	2.7.11.22	0.531
1y8y	CT7	Cyclin-dependent kinase 2	2.7.11.22	0.528
2r3o	2SC	Cyclin-dependent kinase 2	2.7.11.22	0.526
3qts	X46	Cyclin-dependent kinase 2	2.7.11.22	0.524
4fks	46K	Cyclin-dependent kinase 2	2.7.11.22	0.523
3r9d	X6B	Cyclin-dependent kinase 2	2.7.11.22	0.519
4fkl	CK2	Cyclin-dependent kinase 2	2.7.11.22	0.518
3r71	X86	Cyclin-dependent kinase 2	2.7.11.22	0.517
2vtj	LZ4	Cyclin-dependent kinase 2	2.7.11.22	0.516
3igg	EFQ	Cyclin-dependent kinase 2	2.7.11.22	0.515
3rpv	26Z	Cyclin-dependent kinase 2	2.7.11.22	0.515
3r1y	X76	Cyclin-dependent kinase 2	2.7.11.22	0.513
4ek8	16K	Cyclin-dependent kinase 2	2.7.11.22	0.513
3rak	03Z	Cyclin-dependent kinase 2	2.7.11.22	0.509
3r8v	Z62	Cyclin-dependent kinase 2	2.7.11.22	0.508
4fkr	45K	Cyclin-dependent kinase 2	2.7.11.22	0.507
3ezv	EZV	Cyclin-dependent kinase 2	2.7.11.22	0.506
2r3m	SCX	Cyclin-dependent kinase 2	2.7.11.22	0.504
3qxo	X65	Cyclin-dependent kinase 2	2.7.11.22	0.502
4fkq	42K	Cyclin-dependent kinase 2	2.7.11.22	0.500
3r73	X87	Cyclin-dependent kinase 2	2.7.11.22	0.499
1ke5	LS1	Cyclin-dependent kinase 2	2.7.11.22	0.498
3qtu	X44	Cyclin-dependent kinase 2	2.7.11.22	0.498
2fvd	LIA	Cyclin-dependent kinase 2	2.7.11.22	0.497
3rah	O1Z	Cyclin-dependent kinase 2	2.7.11.22	0.497
2j9m	PY8	Cyclin-dependent kinase 2	2.7.11.22	0.496
3rpy	27Z	Cyclin-dependent kinase 2	2.7.11.22	0.496
3s1h	56Z	Cyclin-dependent kinase 2	2.7.11.22	0.495
3rmf	20Z	Cyclin-dependent kinase 2	2.7.11.22	0.494
1pxm	CK5	Cyclin-dependent kinase 2	2.7.11.22	0.493
2r3j	SCJ	Cyclin-dependent kinase 2	2.7.11.22	0.493
3r9n	Z68	Cyclin-dependent kinase 2	2.7.11.22	0.493
3rm7	19Z	Cyclin-dependent kinase 2	2.7.11.22	0.493
3sw7	19K	Cyclin-dependent kinase 2	2.7.11.22	0.491
3qtx	X43	Cyclin-dependent kinase 2	2.7.11.22	0.490
4bgh	3I6	Cyclin-dependent kinase 2	2.7.11.22	0.490
1oit	HDT	Cyclin-dependent kinase 2	2.7.11.22	0.489
1p2a	5BN	Cyclin-dependent kinase 2	2.7.11.22	0.489
2bts	U32	Cyclin-dependent kinase 2	2.7.11.22	0.488
4acm	7YG	Cyclin-dependent kinase 2	2.7.11.22	0.488
2c6m	DT5	Cyclin-dependent kinase 2	2.7.11.22	0.486
2r3l	SCW	Cyclin-dependent kinase 2	2.7.11.22	0.486
1h0w	207	Cyclin-dependent kinase 2	2.7.11.22	0.485
2vts	LZC	Cyclin-dependent kinase 2	2.7.11.22	0.485
2c69	CT8	Cyclin-dependent kinase 2	2.7.11.22	0.484
3rai	X85	Cyclin-dependent kinase 2	2.7.11.22	0.484
1h0v	UN4	Cyclin-dependent kinase 2	2.7.11.22	0.483
1w0x	OLO	Cyclin-dependent kinase 2	2.7.11.22	0.483
3ral	04Z	Cyclin-dependent kinase 2	2.7.11.22	0.482
3sw4	18K	Cyclin-dependent kinase 2	2.7.11.22	0.482
3qxp	X64	Cyclin-dependent kinase 2	2.7.11.22	0.479
2w05	FRT	Cyclin-dependent kinase 2	2.7.11.22	0.478
2xmy	CDK	Cyclin-dependent kinase 2	2.7.11.22	0.477
4btj	ATP	Tau-tubulin kinase 1	2.7.11.1	0.476
1ykr	628	Cyclin-dependent kinase 2	2.7.11.22	0.475
2c6o	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.475
2uzo	C62	Cyclin-dependent kinase 2	2.7.11.22	0.475
3qqh	X0A	Cyclin-dependent kinase 2	2.7.11.22	0.475
4ek6	10K	Cyclin-dependent kinase 2	2.7.11.22	0.475
1b39	ATP	Cyclin-dependent kinase 2	2.7.11.22	0.474
4fko	20K	Cyclin-dependent kinase 2	2.7.11.22	0.474
1fvv	107	Cyclin-dependent kinase 2	2.7.11.22	0.473
2uzn	C96	Cyclin-dependent kinase 2	2.7.11.22	0.473
2r3g	SC9	Cyclin-dependent kinase 2	2.7.11.22	0.472
2r3k	SCQ	Cyclin-dependent kinase 2	2.7.11.22	0.471
2vti	LZ3	Cyclin-dependent kinase 2	2.7.11.22	0.471
1pxo	CK7	Cyclin-dependent kinase 2	2.7.11.22	0.466
2vtp	LZ9	Cyclin-dependent kinase 2	2.7.11.22	0.466
3r8l	Z30	Cyclin-dependent kinase 2	2.7.11.22	0.465
2w17	I19	Cyclin-dependent kinase 2	2.7.11.22	0.463
2c6k	DT2	Cyclin-dependent kinase 2	2.7.11.22	0.462
4fx3	60K	Cyclin-dependent kinase 2	2.7.11.22	0.462
1urw	I1P	Cyclin-dependent kinase 2	2.7.11.22	0.461
2b52	D42	Cyclin-dependent kinase 2	2.7.11.22	0.461
3qru	X19	Cyclin-dependent kinase 2	2.7.11.22	0.461
3qzg	X67	Cyclin-dependent kinase 2	2.7.11.22	0.461
3r7v	Z02	Cyclin-dependent kinase 2	2.7.11.22	0.460
4fkp	LS5	Cyclin-dependent kinase 2	2.7.11.22	0.460
3rjc	06Z	Cyclin-dependent kinase 2	2.7.11.22	0.459
3qwj	X6A	Cyclin-dependent kinase 2	2.7.11.22	0.458
3my5	RFZ	Cyclin-dependent kinase 2	2.7.11.22	0.457
3r9h	Z67	Cyclin-dependent kinase 2	2.7.11.22	0.457
1gih	1PU	Cyclin-dependent kinase 2	2.7.11.22	0.456
3qx2	X63	Cyclin-dependent kinase 2	2.7.11.22	0.456
4nj3	2KD	Cyclin-dependent kinase 2	2.7.11.22	0.456
2a0c	CK9	Cyclin-dependent kinase 2	2.7.11.22	0.455
2w06	FRV	Cyclin-dependent kinase 2	2.7.11.22	0.455
3fz1	B98	Cyclin-dependent kinase 2	2.7.11.22	0.455
3qzf	X66	Cyclin-dependent kinase 2	2.7.11.22	0.455
3s2p	PMU	Cyclin-dependent kinase 2	2.7.11.22	0.455
4fkw	62K	Cyclin-dependent kinase 2	2.7.11.22	0.455
2vth	LZ2	Cyclin-dependent kinase 2	2.7.11.22	0.454
3r7y	Z04	Cyclin-dependent kinase 2	2.7.11.22	0.454
4fki	09K	Cyclin-dependent kinase 2	2.7.11.22	0.453
2exm	ZIP	Cyclin-dependent kinase 2	2.7.11.22	0.451
1y91	CT9	Cyclin-dependent kinase 2	2.7.11.22	0.450
3qtz	X42	Cyclin-dependent kinase 2	2.7.11.22	0.450
3r1s	X73	Cyclin-dependent kinase 2	2.7.11.22	0.450
1gii	1PU	Cyclin-dependent kinase 2	2.7.11.22	0.449
3rni	21Z	Cyclin-dependent kinase 2	2.7.11.22	0.449
3s00	Z60	Cyclin-dependent kinase 2	2.7.11.22	0.449
4kd1	1QK	Cyclin-dependent kinase 2	2.7.11.22	0.449
3ezr	EZR	Cyclin-dependent kinase 2	2.7.11.22	0.448
3qu0	X40	Cyclin-dependent kinase 2	2.7.11.22	0.446
3r83	Z14	Cyclin-dependent kinase 2	2.7.11.22	0.446
4fkv	61K	Cyclin-dependent kinase 2	2.7.11.22	0.444
3r8u	Z31	Cyclin-dependent kinase 2	2.7.11.22	0.443
3unk	0BY	Cyclin-dependent kinase 2	2.7.11.22	0.443
1b38	ATP	Cyclin-dependent kinase 2	2.7.11.22	0.442
1pxp	CK8	Cyclin-dependent kinase 2	2.7.11.22	0.442
2wih	P48	Cyclin-dependent kinase 2	2.7.11.22	0.441
3lfs	A07	Cyclin-dependent kinase 2	2.7.11.22	0.441
3qqk	X02	Cyclin-dependent kinase 2	2.7.11.22	0.441
3qtr	X36	Cyclin-dependent kinase 2	2.7.11.22	0.440
3qzh	X69	Cyclin-dependent kinase 2	2.7.11.22	0.440