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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5kczNAJAlcohol dehydrogenase E chain1.1.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5kczNAJAlcohol dehydrogenase E chain1.1.1.11.000
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.932
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.915
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.874
5kjeNAJAlcohol dehydrogenase E chain1.1.1.10.852
3oq6NAJAlcohol dehydrogenase E chain1.1.1.10.841
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.775
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.771
4nfhNAJAlcohol dehydrogenase E chain1.1.1.10.743
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.689
5cdgNAJAlcohol dehydrogenase E chain1.1.1.10.673
1hetNADAlcohol dehydrogenase E chain1.1.1.10.671
5kcpNAJAlcohol dehydrogenase E chain1.1.1.10.667
4dxhNAJAlcohol dehydrogenase E chain1.1.1.10.654
5cdtNAJAlcohol dehydrogenase E chain1.1.1.10.645
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.637
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.635
2ohxNADAlcohol dehydrogenase E chain1.1.1.10.626
1ht0NADAlcohol dehydrogenase 1C1.1.1.10.620
1hldNADAlcohol dehydrogenase E chain1.1.1.10.619
1ldeNADAlcohol dehydrogenase E chain1.1.1.10.619
5cdsNAJAlcohol dehydrogenase E chain1.1.1.10.617
1heuNADAlcohol dehydrogenase E chain1.1.1.10.615
1a71NADAlcohol dehydrogenase E chain1.1.1.10.613
2oxiNADAlcohol dehydrogenase E chain1.1.1.10.601
5kj1NAJAlcohol dehydrogenase E chain1.1.1.10.600
1hf3NADAlcohol dehydrogenase E chain1.1.1.10.598
2jhfNADAlcohol dehydrogenase E chain1.1.1.10.595
1hszNADAlcohol dehydrogenase 1B1.1.1.10.589
1adcPADAlcohol dehydrogenase E chain1.1.1.10.588
1adbCNDAlcohol dehydrogenase E chain1.1.1.10.585
1u3vNADAlcohol dehydrogenase 1B1.1.1.10.583
6adhNADAlcohol dehydrogenase E chain1.1.1.10.580
1axeNADAlcohol dehydrogenase E chain1.1.1.10.578
1agnNADAlcohol dehydrogenase class 4 mu/sigma chain1.1.1.10.573
1axgNADAlcohol dehydrogenase E chain1.1.1.10.567
3jv7NADSecondary alcohol dehydrogenase/0.567
1mp0NADAlcohol dehydrogenase class-31.1.1.10.564
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.537
4c4oNADSADH/0.532
2fzwNADAlcohol dehydrogenase class-31.1.1.10.531
1ma0NADAlcohol dehydrogenase class-31.1.1.10.527
2dphNADFormaldehyde dismutase/0.527
4dlbNADS-(hydroxymethyl)glutathione dehydrogenase/0.524
4cpdNADAlcohol dehydrogenase/0.522
4rquNADAlcohol dehydrogenase class-P/0.519
3cosNADAlcohol dehydrogenase 41.1.1.10.518
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.516
3wleNAD(R)-specific carbonyl reductase/0.516
4gl4NAIAlcohol dehydrogenase class-3/0.513
1e3lNADAlcohol dehydrogenase 41.1.1.10.512
1kolNADGlutathione-independent formaldehyde dehydrogenase/0.510
4jjiNADAlcohol dehydrogenase class-3/0.508
1h2bNAJNAD-dependent alcohol dehydrogenase/0.502
1e3eNAIAlcohol dehydrogenase 41.1.1.10.501
4dl9NADS-(hydroxymethyl)glutathione dehydrogenase/0.499
1a72PADAlcohol dehydrogenase E chain1.1.1.10.498
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.497
1cdoNADAlcohol dehydrogenase 11.1.1.10.493
2xaaNADSecondary alcohol dehydrogenase/0.491
1lluNADAlcohol dehydrogenase/0.489
1tehNADAlcohol dehydrogenase class-31.1.1.10.483
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.482
5jlaNADPutative short-chain dehydrogenase/reductase/0.481
1f8fNADBenzyl alcohol dehydrogenase/0.479
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.477
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.473
3twoNDPMannitol dehydrogenase/0.471
4w6z8IDAlcohol dehydrogenase 11.1.1.10.467
1r37NADNAD-dependent alcohol dehydrogenase1.1.1.10.463
3toxNAPPutative oxidoreductase/0.462
1ipeNDPTropinone reductase 21.1.1.2360.460
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.459
4j7uNAPSepiapterin reductase1.1.1.1530.458
5envNADAlcohol dehydrogenase 11.1.1.10.458
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.458
2yutNAPPutative short-chain oxidoreductase/0.457
1ae1NAPTropinone reductase 1/0.456
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.456
3ukoNADAlcohol dehydrogenase class-3/0.454
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
2y05NAPProstaglandin reductase 1/0.449
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.449
5idwNAPShort-chain dehydrogenase/reductase SDR/0.449
3gegNADShort-chain dehydrogenase/reductase SDR/0.448
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.448
1dapNDPMeso-diaminopimelate D-dehydrogenase1.4.1.160.447
1kevNDPNADP-dependent isopropanol dehydrogenase1.1.1.800.447
4oknNAIL-lactate dehydrogenase A chain1.1.1.270.447
1nffNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.445
3qrwNDPPutative ketoacyl reductase1.3.10.444
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.444
1yb5NAPQuinone oxidoreductase1.6.5.50.443
1ybmNAPUncharacterized protein At5g02240/0.443
1yqxNAPSinapyl alcohol dehydrogenase/0.443
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.442
1mg5NAIAlcohol dehydrogenase1.1.1.10.442
5dp2NAPCurF/0.442
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.441