sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 1.000 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.665 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.544 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.520 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.514 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.504 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.500 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.480 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.475 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.472 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.469 | |
| 2hwu | URI | Uridine phosphorylase | 2.4.2.3 | 0.469 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.462 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.462 | |
| 1zdw | FLV | Prenyltransferase | / | 0.461 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.460 | |
| 4aza | MGO | Eukaryotic translation initiation factor 4E | / | 0.460 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.458 | |
| 4y1b | NAP | AntE | / | 0.458 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.456 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.455 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.455 | |
| 3c74 | ANU | Uridine phosphorylase | 2.4.2.3 | 0.455 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.454 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.452 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.450 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.450 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.448 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.448 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.443 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.442 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4iae | 1DX | Alr2278 protein | / | 0.442 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.440 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 |