Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ed1 | GA3 | Gibberellin receptor GID1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 1.000 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.668 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.635 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.596 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.483 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.475 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.473 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.473 | |
| 5iqf | GDP | Bifunctional AAC/APH | 2.3.1 | 0.472 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.467 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.467 | |
| 3spt | UD1 | Bifunctional protein GlmU | / | 0.465 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.465 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.462 | |
| 2vut | NAD | Nitrogen metabolite repression protein nmrA | / | 0.461 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.460 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.458 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.457 | |
| 4m2b | UPG | UDP-glucose pyrophosphorylase | / | 0.457 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.455 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.454 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.453 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.453 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.452 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.452 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.451 | |
| 4yqf | GDP | Septin-9 | / | 0.451 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.450 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.449 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.449 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.448 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.446 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.446 | |
| 2vuu | NAP | Nitrogen metabolite repression protein nmrA | / | 0.446 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.446 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.445 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.445 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.444 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.444 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.443 | |
| 1ty9 | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.443 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.442 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.442 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.442 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.442 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.442 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.442 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.441 | |
| 4h6p | FMN | Chromate reductase | / | 0.441 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.440 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.440 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.440 |