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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ed1GA3Gibberellin receptor GID1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3ed1GA3Gibberellin receptor GID1/1.000
3eblGA4Gibberellin receptor GID1/0.668
2zshGA3Gibberellin receptor GID1A30.635
2zsiGA4Gibberellin receptor GID1A30.596
4en4ATPPyridoxal kinase2.7.1.350.483
3hk1B64Fatty acid-binding protein, adipocyte/0.475
2ql6ADPNicotinamide riboside kinase 1/0.473
3d8vUD1Bifunctional protein GlmU/0.473
5iqfGDPBifunctional AAC/APH2.3.10.472
1i59ANPChemotaxis protein CheA2.7.13.30.467
2ejvNADL-threonine 3-dehydrogenase/0.467
3sptUD1Bifunctional protein GlmU/0.465
3t4eNADQuinate/shikimate dehydrogenase/0.465
1fmjRTLRetinol dehydratase/0.462
2vutNADNitrogen metabolite repression protein nmrA/0.461
2nnqT4BFatty acid-binding protein, adipocyte/0.460
1kvtUPGUDP-glucose 4-epimerase5.1.3.20.458
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.458
2gevCOKPantothenate kinase2.7.1.330.457
3junAJDPhenazine biosynthesis protein A/B/0.457
4m2bUPGUDP-glucose pyrophosphorylase/0.457
2v5aLZLBiotin carboxylase6.3.4.140.456
1b2lNDCAlcohol dehydrogenase1.1.1.10.455
3oqfS51Renin3.4.23.150.454
2xfsJ01Uncharacterized protein/0.453
3gfbNADL-threonine 3-dehydrogenase/0.453
3p62FMNPentaerythritol tetranitrate reductase/0.453
3to3ATPPetrobactin biosynthesis protein AsbB/0.453
2x0rNADMalate dehydrogenase/0.452
3oqkS52Renin3.4.23.150.452
3otwCOAPhosphopantetheine adenylyltransferase/0.452
3lqfNADGalactitol dehydrogenase/0.451
3nx4NAPPutative oxidoreductase/0.451
4yqfGDPSeptin-9/0.451
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.450
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.450
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.450
2v58LZJBiotin carboxylase6.3.4.140.450
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.450
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
4bb3KKAIsopenicillin N synthase1.21.3.10.450
1bwsNDPGDP-L-fucose synthase/0.449
1hfqMOTDihydrofolate reductase1.5.1.30.449
1vyrFMNPentaerythritol tetranitrate reductase/0.449
2qo9ANPEphrin type-A receptor 32.7.10.10.449
2yxuATPPyridoxal kinase2.7.1.350.449
3fp0FP015-O-acetyltransferase/0.449
3junAKDPhenazine biosynthesis protein A/B/0.449
3qfcNAPNADPH--cytochrome P450 reductase/0.449
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
2abbFMNPentaerythritol tetranitrate reductase/0.448
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.448
2uxoTACHTH-type transcriptional regulator TtgR/0.447
4fm80UQBeta-secretase 13.4.23.460.447
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.447
1h50FMNPentaerythritol tetranitrate reductase/0.446
2g1n1IGRenin3.4.23.150.446
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.446
2vuuNAPNitrogen metabolite repression protein nmrA/0.446
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.446
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
4bfsZVSPantothenate kinase2.7.1.330.446
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.446
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.445
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.445
4fxfATPPyruvate kinase PKM2.7.1.400.445
1dhrNADDihydropteridine reductase1.5.1.340.444
1f20NAPNitric oxide synthase, brain1.14.13.390.444
1j39UPGDNA beta-glucosyltransferase/0.444
3f03FMNPentaerythritol tetranitrate reductase/0.444
4b3aTACTetracycline repressor protein class D/0.444
4i6gFADCryptochrome-2/0.444
4itmATPTetraacyldisaccharide 4'-kinase/0.444
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.443
1ty9FMNPhenazine biosynthesis protein PhzG1.40.443
1omoNADAlanine dehydrogenase/0.442
2lbaCHOFatty acid binding protein 6/0.442
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.442
4isk1JYThymidylate synthase/0.442
4jbiNDPAlcohol dehydrogenase (Zinc)/0.442
4kgmATPUncharacterized protein/0.442
4m9aFDAAcyl-CoA dehydrogenase/0.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.441
1towCRZFatty acid-binding protein, adipocyte/0.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441
3ibqATPPyridoxal kinase/0.441
4h6pFMNChromate reductase/0.441
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.440
1gtrATPGlutamine--tRNA ligase6.1.1.180.440
1rywEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.440
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.440
3cisATPUniversal stress protein Rv2623/0.440
3h3sH15Collagen type IV alpha-3-binding protein/0.440