scPDB - Distribution of Binding site Similarity values of 2vu3 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2vu3	LZE	Cyclin-dependent kinase 2	2.7.11.22

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2vu3	LZE	Cyclin-dependent kinase 2	2.7.11.22	1.000
2fvd	LIA	Cyclin-dependent kinase 2	2.7.11.22	0.602
2vtt	LZD	Cyclin-dependent kinase 2	2.7.11.22	0.548
4bcm	T7Z	Cyclin-dependent kinase 2	2.7.11.22	0.543
3rak	03Z	Cyclin-dependent kinase 2	2.7.11.22	0.540
3qxp	X64	Cyclin-dependent kinase 2	2.7.11.22	0.527
1ke7	LS3	Cyclin-dependent kinase 2	2.7.11.22	0.519
4erw	STU	Cyclin-dependent kinase 2	2.7.11.22	0.514
2w05	FRT	Cyclin-dependent kinase 2	2.7.11.22	0.512
3r9d	X6B	Cyclin-dependent kinase 2	2.7.11.22	0.507
1ke6	LS2	Cyclin-dependent kinase 2	2.7.11.22	0.506
3rm6	18Z	Cyclin-dependent kinase 2	2.7.11.22	0.506
1ke5	LS1	Cyclin-dependent kinase 2	2.7.11.22	0.502
3lfn	A27	Cyclin-dependent kinase 2	2.7.11.22	0.502
4ez5	0RS	Cyclin-dependent kinase 6	2.7.11.22	0.502
3qtu	X44	Cyclin-dependent kinase 2	2.7.11.22	0.500
3s1h	56Z	Cyclin-dependent kinase 2	2.7.11.22	0.496
1g5s	I17	Cyclin-dependent kinase 2	2.7.11.22	0.495
1pxm	CK5	Cyclin-dependent kinase 2	2.7.11.22	0.492
1fvv	107	Cyclin-dependent kinase 2	2.7.11.22	0.487
1oiy	N41	Cyclin-dependent kinase 2	2.7.11.22	0.487
3r9h	Z67	Cyclin-dependent kinase 2	2.7.11.22	0.485
2vtp	LZ9	Cyclin-dependent kinase 2	2.7.11.22	0.483
3rkb	12Z	Cyclin-dependent kinase 2	2.7.11.22	0.482
4mq1	2C3	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	2.7.12.1	0.482
3qxo	X65	Cyclin-dependent kinase 2	2.7.11.22	0.481
1aq1	STU	Cyclin-dependent kinase 2	2.7.11.22	0.480
3ig7	EFP	Cyclin-dependent kinase 2	2.7.11.22	0.478
3r8l	Z30	Cyclin-dependent kinase 2	2.7.11.22	0.478
2vtq	LZA	Cyclin-dependent kinase 2	2.7.11.22	0.476
3rpv	26Z	Cyclin-dependent kinase 2	2.7.11.22	0.475
1gih	1PU	Cyclin-dependent kinase 2	2.7.11.22	0.474
1ke8	LS4	Cyclin-dependent kinase 2	2.7.11.22	0.474
3ezr	EZR	Cyclin-dependent kinase 2	2.7.11.22	0.473
3i4b	Z48	Glycogen synthase kinase-3 beta	2.7.11.26	0.473
3qru	X19	Cyclin-dependent kinase 2	2.7.11.22	0.473
3rpo	24Z	Cyclin-dependent kinase 2	2.7.11.22	0.472
2bts	U32	Cyclin-dependent kinase 2	2.7.11.22	0.470
3rm7	19Z	Cyclin-dependent kinase 2	2.7.11.22	0.469
1pkd	UCN	Cyclin-dependent kinase 2	2.7.11.22	0.468
3sqq	99Z	Cyclin-dependent kinase 2	2.7.11.22	0.468
2w06	FRV	Cyclin-dependent kinase 2	2.7.11.22	0.467
3r1s	X73	Cyclin-dependent kinase 2	2.7.11.22	0.467
2c4g	514	Cyclin-dependent kinase 2	2.7.11.22	0.466
3r83	Z14	Cyclin-dependent kinase 2	2.7.11.22	0.466
3i60	E86	Mitogen-activated protein kinase 1	2.7.11.24	0.465
3qx2	X63	Cyclin-dependent kinase 2	2.7.11.22	0.465
2iw8	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.463
2w17	I19	Cyclin-dependent kinase 2	2.7.11.22	0.463
3ddp	RC8	Cyclin-dependent kinase 2	2.7.11.22	0.463
3rk9	09Z	Cyclin-dependent kinase 2	2.7.11.22	0.463
4fkv	61K	Cyclin-dependent kinase 2	2.7.11.22	0.463
2iw9	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.462
3r28	XA0	Cyclin-dependent kinase 2	2.7.11.22	0.462
3ddq	RRC	Cyclin-dependent kinase 2	2.7.11.22	0.461
3f69	XDR	Serine/threonine-protein kinase PknB	2.7.11.1	0.461
3r73	X87	Cyclin-dependent kinase 2	2.7.11.22	0.461
3r7y	Z04	Cyclin-dependent kinase 2	2.7.11.22	0.461
3rni	21Z	Cyclin-dependent kinase 2	2.7.11.22	0.461
4bch	T7Z	Cyclin-dependent kinase 9	2.7.11.22	0.461
4bgh	3I6	Cyclin-dependent kinase 2	2.7.11.22	0.461
2vv9	IM9	Cyclin-dependent kinase 2	2.7.11.22	0.460
3qqk	X02	Cyclin-dependent kinase 2	2.7.11.22	0.460
4fx3	60K	Cyclin-dependent kinase 2	2.7.11.22	0.460
4agu	D15	Cyclin-dependent kinase-like 1	/	0.459
1h1r	6CP	Cyclin-dependent kinase 2	2.7.11.22	0.458
3sw7	19K	Cyclin-dependent kinase 2	2.7.11.22	0.457
4fv9	E71	Mitogen-activated protein kinase 1	2.7.11.24	0.457
1ogu	ST8	Cyclin-dependent kinase 2	2.7.11.22	0.456
1pye	PM1	Cyclin-dependent kinase 2	2.7.11.22	0.456
2c6i	DT1	Cyclin-dependent kinase 2	2.7.11.22	0.456
3my5	RFZ	Cyclin-dependent kinase 2	2.7.11.22	0.456
3qzg	X67	Cyclin-dependent kinase 2	2.7.11.22	0.456
3rk7	08Z	Cyclin-dependent kinase 2	2.7.11.22	0.456
4kd1	1QK	Cyclin-dependent kinase 2	2.7.11.22	0.456
3u4u	LNH	Casein kinase II subunit alpha	2.7.11.1	0.455
2b52	D42	Cyclin-dependent kinase 2	2.7.11.22	0.454
1h1s	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.453
3roy	22Z	Cyclin-dependent kinase 2	2.7.11.22	0.453
1w8c	N69	Cyclin-dependent kinase 2	2.7.11.22	0.452
3qu0	X40	Cyclin-dependent kinase 2	2.7.11.22	0.451
3r8p	Z46	Cyclin-dependent kinase 2	2.7.11.22	0.451
1di8	DTQ	Cyclin-dependent kinase 2	2.7.11.22	0.450
2uzo	C62	Cyclin-dependent kinase 2	2.7.11.22	0.450
3mfs	ANP	Peripheral plasma membrane protein CASK	2.7.11.1	0.450
3r6x	X84	Cyclin-dependent kinase 2	2.7.11.22	0.450
4bcn	T9N	Cyclin-dependent kinase 2	2.7.11.22	0.450
3amb	VX6	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.449
3nup	3NU	Cyclin-dependent kinase 6	2.7.11.22	0.449
3qtr	X36	Cyclin-dependent kinase 2	2.7.11.22	0.449
3qwj	X6A	Cyclin-dependent kinase 2	2.7.11.22	0.449
3s0o	50Z	Cyclin-dependent kinase 2	2.7.11.22	0.449
3qzh	X69	Cyclin-dependent kinase 2	2.7.11.22	0.447
3c0g	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.446
3r1q	X75	Cyclin-dependent kinase 2	2.7.11.22	0.446
3ral	04Z	Cyclin-dependent kinase 2	2.7.11.22	0.446
4bcq	TJF	Cyclin-dependent kinase 2	2.7.11.22	0.446
1p2a	5BN	Cyclin-dependent kinase 2	2.7.11.22	0.445
3lfs	A07	Cyclin-dependent kinase 2	2.7.11.22	0.445
1ykr	628	Cyclin-dependent kinase 2	2.7.11.22	0.444
3rmf	20Z	Cyclin-dependent kinase 2	2.7.11.22	0.444
3wbl	PDY	Cyclin-dependent kinase 2	2.7.11.22	0.444
4bkz	1WS	Maternal embryonic leucine zipper kinase	2.7.11.1	0.444
4fv3	EK6	Mitogen-activated protein kinase 1	2.7.11.24	0.444
3qtz	X42	Cyclin-dependent kinase 2	2.7.11.22	0.443
3r7v	Z02	Cyclin-dependent kinase 2	2.7.11.22	0.443
2vts	LZC	Cyclin-dependent kinase 2	2.7.11.22	0.442
2zjw	REF	Casein kinase II subunit alpha	2.7.11.1	0.442
3c0i	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.442
3qrt	X14	Cyclin-dependent kinase 2	2.7.11.22	0.442
3r71	X86	Cyclin-dependent kinase 2	2.7.11.22	0.442
3rah	O1Z	Cyclin-dependent kinase 2	2.7.11.22	0.442
4dit	0KD	Glycogen synthase kinase-3 beta	2.7.11.26	0.442
1h0w	207	Cyclin-dependent kinase 2	2.7.11.22	0.441
2b55	D31	Cyclin-dependent kinase 2	2.7.11.22	0.441
2r64	740	Cyclin-dependent kinase 2	2.7.11.22	0.441
2uzb	C75	Cyclin-dependent kinase 2	2.7.11.22	0.441
2vtn	LZ7	Cyclin-dependent kinase 2	2.7.11.22	0.441
3s2p	PMU	Cyclin-dependent kinase 2	2.7.11.22	0.441
1urw	I1P	Cyclin-dependent kinase 2	2.7.11.22	0.440
3r9n	Z68	Cyclin-dependent kinase 2	2.7.11.22	0.440
3zc6	VFC	Tyrosine-protein kinase JAK3	2.7.10.2	0.440