sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.766 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.749 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.704 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.685 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.667 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.664 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.663 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.659 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.658 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.655 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.654 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.653 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.648 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.646 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.646 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.646 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.643 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.642 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.642 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.640 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.640 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.633 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.632 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.631 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.631 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.622 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.618 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.618 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.617 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.610 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.606 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.605 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.604 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.604 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.603 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.599 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.599 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.596 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.586 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.581 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.579 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.569 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.562 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.562 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.557 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.555 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.537 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.532 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.529 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.529 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.527 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.521 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.517 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.504 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.502 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.489 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.487 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.484 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.483 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.483 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.483 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.482 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.480 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.478 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.475 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.474 | |
| 5bmv | VLB | Tubulin alpha-1B chain | / | 0.474 | |
| 5bmv | VLB | Tubulin beta chain | / | 0.474 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.473 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.470 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.469 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.467 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.465 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.463 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.461 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.461 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.461 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.460 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.459 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.458 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.455 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.455 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 2y3s | TIR | TamL | / | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.452 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.450 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.450 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.449 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.449 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.449 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.448 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.447 | |
| 1fml | RTL | Retinol dehydratase | / | 0.446 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 5a3b | APR | SIR2 family protein | / | 0.446 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.445 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.444 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.440 |