Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3sfd FAD Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3sfd FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.604
3sfe FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.370
3aeb FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.232
4yxd FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.231
5c2t FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.224
4ytn FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.162
3ae4 FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.151
5c3j FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.044
1kf6 FADFumarate reductase flavoprotein subunit 1.3.5.4 0.989
4kx6 FADFumarate reductase flavoprotein subunit 1.3.5.4 0.938
1knp FADL-aspartate oxidase 1.4.3.16 0.911
1knr FADL-aspartate oxidase 1.4.3.16 0.874
2du8 FADD-amino-acid oxidase 1.4.3.3 0.856
3cuk FADD-amino-acid oxidase 1.4.3.3 0.831
1c0l FADD-amino-acid oxidase 1.4.3.3 0.810
4yjd FADD-amino-acid oxidase 1.4.3.3 0.809
1d4c FADFumarate reductase flavoprotein subunit 1.3.5.4 0.805
1c0k FADD-amino-acid oxidase 1.4.3.3 0.804
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.795
1qo8 FADFumarate reductase flavoprotein subunit / 0.794
4opc FDAConserved Archaeal protein / 0.756
1ng3 FADGlycine oxidase 1.4.3.19 0.750
1ryi FADGlycine oxidase 1.4.3.19 0.746
1ng4 FADGlycine oxidase 1.4.3.19 0.740
3axb FADPutative oxidoreductase / 0.739
2c4c FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.736
3vqr FADPutative oxidoreductase / 0.736
3znp FADD-amino-acid oxidase 1.4.3.3 0.735
4x9n FADUncharacterized protein MG039 homolog / 0.734
5ez7 FADProbable FAD-dependent oxidoreductase PA4991 / 0.729
4xwz FADFructosyl amine:oxygen oxidoreductase / 0.724
1kif FADD-amino-acid oxidase 1.4.3.3 0.721
1ve9 FADD-amino-acid oxidase 1.4.3.3 0.720
5i39 FADL-amino acid deaminase / 0.717
3ic9 FADPutative dihydrolipoamide dehydrogenase / 0.716
4cnj FADL-amino acid oxidase / 0.714
4opt FDAConserved Archaeal protein / 0.711
5eb5 FAD(R)-mandelonitrile lyase 1 4.1.2.10 0.708
2fzn FADBifunctional protein PutA 1.5.5.2 0.707
4qi5 FADCellobiose dehydrogenase / 0.707
4wct FADFructosyl amine:oxygen oxidoreductase / 0.707
1gal FADGlucose oxidase 1.1.3.4 0.704
1tde FADThioredoxin reductase 1.8.1.9 0.703
3ad9 FADSubunit beta of sarcosine oxidase / 0.703
4hj3 FMNLOV protein / 0.703
4opl FDAConserved Archaeal protein / 0.703
3dme FADPutative conserved exported protein / 0.702
2pr5 FMNBlue-light photoreceptor / 0.701
5hsa FASAlcohol oxidase 1 1.1.3.13 0.701
1xdi FADNAD(P)H dehydrogenase (quinone) / 0.700
4nwz FADFAD-dependent pyridine nucleotide-disulfide oxidoreductase / 0.700
4gdp FADPolyamine oxidase FMS1 / 0.697
3atq FDAConserved Archaeal protein / 0.695
3g5q FADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO / 0.695
3m12 FADMonomeric sarcosine oxidase 1.5.3.1 0.692
1krh FADBenzoate 1,2-dioxygenase electron transfer component 1.18.1.3 0.691
2c3c FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.690
4c3y FAD3-ketosteroid dehydrogenase / 0.690
4qi4 FADCellobiose dehydrogenase / 0.690
1rsg FADPolyamine oxidase FMS1 / 0.689
2dw4 FADLysine-specific histone demethylase 1A 1 0.688
2ard FDAFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.687
3gsi FADDimethylglycine oxidase 1.5.3.10 0.687
4x9m FADUncharacterized protein MG039 homolog / 0.687
4opu FDAConserved Archaeal protein / 0.686
1tj1 FADBifunctional protein PutA 1.5.5.2 0.684
1gth FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.683
4gur FADLysine-specific histone demethylase 1B 1 0.683
3nt6 FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.682
2e1m FADL-glutamate oxidase / 0.681
4hsu FADLysine-specific histone demethylase 1B 1 0.680
2z6d FMNPhototropin-2 2.7.11.1 0.679
4ysh FADGlycine oxidase / 0.678
1tj2 FADBifunctional protein PutA 1.5.5.2 0.677
1siq FADGlutaryl-CoA dehydrogenase, mitochondrial 1.3.8.6 0.676
3atr FDAConserved Archaeal protein / 0.676
3m0o FADMonomeric sarcosine oxidase 1.5.3.1 0.676
4at0 FADPossible succinate dehydrogenase / 0.676
2qcu FADAerobic glycerol-3-phosphate dehydrogenase 1.1.5.3 0.675
5djt FMNNPH1-2 / 0.674
4eep FMNPhototropin-2 2.7.11.1 0.673
4ees FMNPhototropin-2 2.7.11.1 0.672
4udq FAD5-(hydroxymethyl)furfural oxidase / 0.672
1h81 FADPolyamine oxidase 1.5.3.14 0.670
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.669
2ok8 FADFerredoxin--NADP reductase, apicoplast / 0.669
3dk4 FADGlutathione reductase, mitochondrial 1.8.1.7 0.669
3jqr FADFerredoxin--NADP reductase, apicoplast / 0.669
3t2y FADSulfide-quinone reductase / 0.669
4gcm FADThioredoxin reductase 1.8.1.9 0.668
2iw5 FADLysine-specific histone demethylase 1A 1 0.667
3is2 FADVivid PAS protein VVD / 0.667
3mkh FADNitroalkane oxidase / 0.667
2v1a FMNNPH1-1 / 0.666
4eer FMNPhototropin-2 2.7.11.1 0.666
3m13 FADMonomeric sarcosine oxidase 1.5.3.1 0.665
2z6c FMNPhototropin-1 2.7.11.1 0.664
4eet FMNPhototropin-2 2.7.11.1 0.664
4o5u FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.664
3nyc FADFAD-dependent catabolic D-arginine dehydrogenase DauA / 0.663
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.663
4guu FA9Lysine-specific histone demethylase 1B 1 0.663
4opd FDAConserved Archaeal protein / 0.663
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.662
3sm8 FNKFAD-dependent catabolic D-arginine dehydrogenase DauA / 0.662
3rp8 FADFAD-dependent urate hydroxylase / 0.661
3k4n FADPyranose 2-oxidase / 0.660
3ue6 FMNAureochrome1 / 0.660
4xbf FADLysine-specific histone demethylase 1A 1 0.660
2uxx FAJLysine-specific histone demethylase 1A 1 0.659
1tdf FADThioredoxin reductase 1.8.1.9 0.658
1trb FADThioredoxin reductase 1.8.1.9 0.658
2cdu FADNADH oxidase / 0.658
3h5n ATPMccB protein / 0.658
2ba9 FADPutative aminooxidase / 0.657
3t37 FADPyridoxine 4-oxidase / 0.657
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.656
2whd FADThioredoxin reductase / 0.656
4cy8 FDA2-hydroxybiphenyl-3-monooxygenase / 0.655
4udr FAD5-(hydroxymethyl)furfural oxidase / 0.655
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.654
1ps9 FAD2,4-dienoyl-CoA reductase 1.3.1.34 0.654
2h94 FADLysine-specific histone demethylase 1A 1 0.654
3cnt FADPolyamine oxidase FMS1 / 0.654
5dju FMNNPH1-2 / 0.654
2rgh FADAlpha-Glycerophosphate Oxidase / 0.653
3d72 FADVivid PAS protein VVD / 0.653
4ccq FADThioredoxin reductase / 0.653
1efv FADElectron transfer flavoprotein subunit alpha, mitochondrial / 0.652
2q7v FADThioredoxin reductase / 0.652
2y48 FADLysine-specific histone demethylase 1A 1 0.652
3kpf FADPolyamine oxidase 1.5.3.14 0.652
3pl8 FADPyranose 2-oxidase / 0.652
4gut FADLysine-specific histone demethylase 1B 1 0.652
4ykf FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.652
5hxw FADL-amino acid deaminase / 0.652
1yy5 FADPolyamine oxidase FMS1 / 0.651
2yyi FAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component 1.14.14.9 0.651
3lsm SFDPyranose 2-oxidase / 0.651
3p62 FMNPentaerythritol tetranitrate reductase / 0.651
4z43 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.651
1h83 FADPolyamine oxidase 1.5.3.14 0.650
4r38 RBFBlue-light-activated histidine kinase 2 2.7.13.3 0.650
4yry FADGlutamate synthase, beta subunit / 0.650