sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3kcc | CMP | cAMP-activated global transcriptional regulator CRP |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3kcc | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.926 | |
| 4i09 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.914 | |
| 4i0a | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.912 | |
| 4i0b | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.907 | |
| 3ryp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.891 | |
| 4ft8 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.891 | |
| 1i5z | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.890 | |
| 4hzf | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.890 | |
| 3rou | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.887 | |
| 3n4m | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.876 | |
| 3qop | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.874 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.870 | |
| 1g6n | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.865 | |
| 3ryr | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.854 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.850 | |
| 4i01 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.840 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.838 | |
| 4r8h | SP1 | cAMP-activated global transcriptional regulator CRP | / | 0.837 | |
| 3rpq | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.835 | |
| 1hw5 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.832 | |
| 3rdi | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.827 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.821 | |
| 1zrd | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.820 | |
| 2gzw | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.799 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.767 | |
| 1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.762 | |
| 1q5o | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.762 | |
| 3u11 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.760 | |
| 1zrc | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.758 | |
| 3bpz | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.758 | |
| 1q3e | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.756 | |
| 3u10 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.756 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.754 | |
| 4d7t | CMP | Uncharacterized protein | / | 0.752 | |
| 1cx4 | CMP | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.750 | |
| 3cl1 | PCG | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.747 | |
| 4hbn | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.746 | |
| 1cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.744 | |
| 4z07 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.744 | |
| 4ku7 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.739 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.739 | |
| 2ptm | CMP | Hyperpolarization-activated (Ih) channel | / | 0.738 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.737 | |
| 3u0z | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | / | 0.735 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.727 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.726 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.718 | |
| 3shr | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.711 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.710 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.707 | |
| 4d7s | PCG | Uncharacterized protein | / | 0.706 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.704 | |
| 4mgk | CMP | Rap guanine nucleotide exchange factor 4 | / | 0.700 | |
| 3ogj | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.698 | |
| 3plq | RP2 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.695 | |
| 3od0 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.693 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.691 | |
| 5ahw | CMP | Universal stress protein family protein, putative | / | 0.690 | |
| 1ruo | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.688 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.681 | |
| 4c5b | ADP | D-alanine--D-alanine ligase B | 6.3.2.4 | 0.670 | |
| 4c5c | ATP | D-alanine--D-alanine ligase B | 6.3.2.4 | 0.665 | |
| 2k0g | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.662 | |
| 4ev0 | CMP | Cyclic AMP receptor protein | / | 0.662 | |
| 5a7y | SAH | tRNA (adenine(9)-N1)-methyltransferase | 2.1.1.218 | 0.662 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.661 | |
| 2io8 | ADP | Bifunctional glutathionylspermidine synthetase/amidase | / | 0.660 | |
| 3of1 | CMP | cAMP-dependent protein kinase regulatory subunit | / | 0.655 | |
| 4kg1 | PCG | Diguanylate cyclase | / | 0.652 |