sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 1.163 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.787 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.777 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.761 | |
| 1n35 | CH1 | RNA-directed RNA polymerase lambda-3 | 2.7.7.48 | 0.744 | |
| 1n38 | U3H | RNA-directed RNA polymerase lambda-3 | 2.7.7.48 | 0.744 | |
| 1nmd | ATP | Major actin | / | 0.744 | |
| 1wet | GUN | HTH-type transcriptional repressor PurR | / | 0.744 | |
| 1xxj | UNC | Uricase | 1.7.3.3 | 0.744 | |
| 2d09 | FLV | Biflaviolin synthase CYP158A2 | / | 0.744 | |
| 2fzk | CTP | Aspartate carbamoyltransferase regulatory chain | / | 0.744 | |
| 2jey | HLO | Acetylcholinesterase | 3.1.1.7 | 0.744 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.744 | |
| 2z7q | ACP | Ribosomal protein S6 kinase alpha-1 | 2.7.11.1 | 0.744 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.744 | |
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 0.744 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.744 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.744 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.744 | |
| 3u9d | ATP | Actin, alpha skeletal muscle | / | 0.744 | |
| 3ypi | PGH | Triosephosphate isomerase | 5.3.1.1 | 0.744 | |
| 4e5l | DBH | Polymerase acidic protein | / | 0.744 | |
| 5bnt | NAP | Aspartate-semialdehyde dehydrogenase | 1.2.1.11 | 0.744 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.728 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.727 | |
| 3k9v | CPS | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | / | 0.716 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.714 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.714 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.709 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.709 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.707 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.705 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.695 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.694 | |
| 2pit | DHT | Androgen receptor | / | 0.690 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.688 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.678 | |
| 4oea | DHT | Androgen receptor | / | 0.678 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.676 | |
| 2ocf | EST | Estrogen receptor | / | 0.674 | |
| 2ama | DHT | Androgen receptor | / | 0.672 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.672 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.670 | |
| 2k62 | ITL | Fatty acid-binding protein, liver | / | 0.668 | |
| 4oey | DHT | Androgen receptor | / | 0.668 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.664 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.663 | |
| 2j7x | EST | Estrogen receptor beta | / | 0.663 | |
| 2ylp | TES | Androgen receptor | / | 0.663 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.662 | |
| 1t73 | DHT | Androgen receptor | / | 0.661 | |
| 2pio | DHT | Androgen receptor | / | 0.661 | |
| 1h48 | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.660 | |
| 1t5z | DHT | Androgen receptor | / | 0.660 | |
| 1yra | GDP | GPN-loop GTPase PAB0955 | / | 0.660 | |
| 2puf | GUN | HTH-type transcriptional repressor PurR | / | 0.660 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.660 | |
| 3fwy | ADP | Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein | / | 0.660 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.660 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.660 | |
| 4o3m | ADP | Bloom syndrome protein | 3.6.4.12 | 0.660 | |
| 4ofr | DHT | Androgen receptor | / | 0.660 | |
| 1t74 | DHT | Androgen receptor | / | 0.659 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.659 | |
| 2q7i | TES | Androgen receptor | / | 0.659 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.659 | |
| 2mm3 | GCH | Gastrotropin | / | 0.657 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.656 | |
| 3up0 | D7S | aceDAF-12 | / | 0.655 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.655 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.654 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.654 | |
| 3up3 | XCA | aceDAF-12 | / | 0.654 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.652 | |
| 4hlw | TES | Androgen receptor | / | 0.652 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.651 | |
| 2pkl | DHT | Androgen receptor | / | 0.651 | |
| 5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.650 |