Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3a0t ADP Sensor histidine kinase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3a0t ADPSensor histidine kinase / 1.126
1z5c ADPType 2 DNA topoisomerase 6 subunit B / 0.927
3d2r ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.884
2zkj ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.879
1gjv AGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 2.7.11.4 0.851
1z5a ADPType 2 DNA topoisomerase 6 subunit B / 0.832
3sl2 ATPSensor histidine kinase WalK / 0.820
4prv ADPDNA gyrase subunit B / 0.808
1mx0 ANPType 2 DNA topoisomerase 6 subunit B / 0.803
4prx ADPDNA gyrase subunit B / 0.789
2e0a ANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.787
4wuc ANPDNA gyrase subunit B / 0.781
4wud ANPDNA gyrase subunit B / 0.771
1nhh ANPDNA mismatch repair protein MutL / 0.769
2zdy ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.767
4ivg ANPTNF receptor-associated protein 1 / 0.753
1jm6 ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.749
1th8 ADPAnti-sigma F factor / 0.748
1thn ADPAnti-sigma F factor / 0.748
1zxn ADPDNA topoisomerase 2-alpha 5.99.1.3 0.725
3t2s AGSHeat shock protein HSP 90-alpha / 0.721
1z59 ADPType 2 DNA topoisomerase 6 subunit B / 0.714
4ipe ANPTNF receptor-associated protein 1 / 0.713
1id0 ANPSensor protein PhoQ 2.7.13.3 0.711
1i59 ANPChemotaxis protein CheA 2.7.13.3 0.708
3t10 ACPHeat shock protein HSP 90-alpha / 0.707
2qta TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.706
4bix ADPSensor histidine kinase CpxA / 0.704
4r1f ADPDNA topoisomerase 2-alpha 5.99.1.3 0.704
3t1k ANPHeat shock protein HSP 90-alpha / 0.701
1i5a ACPChemotaxis protein CheA 2.7.13.3 0.698
4xcl AGSHeat shock cognate 90 kDa protein / 0.696
2ior ADPChaperone protein HtpG / 0.693
3zkd ANPDNA gyrase subunit B / 0.689
5f5r ANPHeat shock protein 75 kDa, mitochondrial / 0.686
4xc0 ACPHeat shock cognate 90 kDa protein / 0.684
3crl ANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.680
1i5b ANPChemotaxis protein CheA 2.7.13.3 0.679
2c2a ADPSensor histidine kinase / 0.679
3zkb ANPDNA gyrase subunit B / 0.677
4xcj ADPHeat shock cognate 90 kDa protein / 0.677
1g4p FQPThiamine-phosphate synthase / 0.672
3t0z ATPHeat shock protein HSP 90-alpha / 0.672
5c93 ACPTwo-component system histidine protein kinase / 0.672
3h4l ANPDNA mismatch repair protein PMS1 / 0.670
2h2a DNDProbable nicotinate-nucleotide adenylyltransferase / 0.667
4gm1 TZDBenzoylformate decarboxylase 4.1.1.7 0.664
4jau ADPSensor histidine kinase / 0.664
4gm4 TZDBenzoylformate decarboxylase 4.1.1.7 0.662
1bfd TPPBenzoylformate decarboxylase 4.1.1.7 0.660
2c3y HTLPyruvate synthase / 0.660
4gqt ADPHeat shock protein 90 / 0.658
1pvg ANPDNA topoisomerase 2 5.99.1.3 0.653
1s16 ANPDNA topoisomerase 4 subunit B / 0.653
1i58 ACPChemotaxis protein CheA 2.7.13.3 0.652
3v2u ATPProtein GAL3 / 0.652
1rp7 TZDPyruvate dehydrogenase E1 component 1.2.4.1 0.651
1ei1 ANPDNA gyrase subunit B / 0.650