sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.000 | |
| 3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.637 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.628 | |
| 3nhj | A2Z | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.627 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.619 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.619 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.616 | |
| 3owx | XRA | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.615 | |
| 4zvm | DM2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.615 | |
| 4fgj | 1PQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.609 | |
| 3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.600 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.589 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.587 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.586 | |
| 3nfr | EWQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.585 | |
| 3nhr | RZW | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.585 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.583 | |
| 1xi2 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.579 | |
| 4gr9 | 372 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.579 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.569 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.566 | |
| 4qoh | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.566 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.565 | |
| 3nhu | M42 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.556 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.551 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.551 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.545 | |
| 4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.523 | |
| 3gam | MXX | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.521 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.519 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.517 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.505 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.463 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 2qjp | ANJ | Cytochrome b | / | 0.458 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.456 | |
| 2ycy | P32 | Beta-1 adrenergic receptor | / | 0.456 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 3arv | SAU | Chitinase A | / | 0.447 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.446 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.441 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 |