sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2v5a	LZL	Biotin carboxylase	6.3.4.14

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2v5a	LZL	Biotin carboxylase	6.3.4.14	1.000
2v58	LZJ	Biotin carboxylase	6.3.4.14	0.542
3jzf	JZK	Biotin carboxylase	6.3.4.14	0.508
2w6n	OA2	Biotin carboxylase	6.3.4.14	0.495
2w6q	OA5	Biotin carboxylase	6.3.4.14	0.494
2vr1	ATF	Biotin carboxylase	6.3.4.14	0.473
4mv1	ADP	Biotin carboxylase	6.3.4.14	0.458
2v59	LZK	Biotin carboxylase	6.3.4.14	0.455
2w6m	OA1	Biotin carboxylase	6.3.4.14	0.451
4mv8	ACP	Biotin carboxylase	6.3.4.14	0.445
2w6z	L21	Biotin carboxylase	6.3.4.14	0.444
2w6o	OA3	Biotin carboxylase	6.3.4.14	0.443