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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c6o4SPCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2c6o4SPCyclin-dependent kinase 22.7.11.221.000
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.557
3r7yZ04Cyclin-dependent kinase 22.7.11.220.552
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.549
1oitHDTCyclin-dependent kinase 22.7.11.220.547
2uzoC62Cyclin-dependent kinase 22.7.11.220.543
1w8cN69Cyclin-dependent kinase 22.7.11.220.540
3lfqA28Cyclin-dependent kinase 22.7.11.220.538
3r8lZ30Cyclin-dependent kinase 22.7.11.220.538
3lfnA27Cyclin-dependent kinase 22.7.11.220.535
2a0cCK9Cyclin-dependent kinase 22.7.11.220.530
1pxmCK5Cyclin-dependent kinase 22.7.11.220.527
2btrU73Cyclin-dependent kinase 22.7.11.220.519
3qzgX67Cyclin-dependent kinase 22.7.11.220.517
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.511
2vthLZ2Cyclin-dependent kinase 22.7.11.220.509
4ek610KCyclin-dependent kinase 22.7.11.220.508
3iggEFQCyclin-dependent kinase 22.7.11.220.506
4fkq42KCyclin-dependent kinase 22.7.11.220.506
2btsU32Cyclin-dependent kinase 22.7.11.220.505
3r1yX76Cyclin-dependent kinase 22.7.11.220.505
3r8vZ62Cyclin-dependent kinase 22.7.11.220.504
4fkt48KCyclin-dependent kinase 22.7.11.220.504
1ke6LS2Cyclin-dependent kinase 22.7.11.220.503
4ek816KCyclin-dependent kinase 22.7.11.220.503
3qqlX03Cyclin-dependent kinase 22.7.11.220.502
2r3jSCJCyclin-dependent kinase 22.7.11.220.501
1pxoCK7Cyclin-dependent kinase 22.7.11.220.499
4fkpLS5Cyclin-dependent kinase 22.7.11.220.499
3r9dX6BCyclin-dependent kinase 22.7.11.220.498
4kd11QKCyclin-dependent kinase 22.7.11.220.498
1ke5LS1Cyclin-dependent kinase 22.7.11.220.497
3r7vZ02Cyclin-dependent kinase 22.7.11.220.495
3r83Z14Cyclin-dependent kinase 22.7.11.220.495
3rahO1ZCyclin-dependent kinase 22.7.11.220.495
1ke7LS3Cyclin-dependent kinase 22.7.11.220.494
2exmZIPCyclin-dependent kinase 22.7.11.220.494
3qwjX6ACyclin-dependent kinase 22.7.11.220.494
1oirHDYCyclin-dependent kinase 22.7.11.220.491
3s2pPMUCyclin-dependent kinase 22.7.11.220.490
3r71X86Cyclin-dependent kinase 22.7.11.220.487
1y8yCT7Cyclin-dependent kinase 22.7.11.220.484
2c6kDT2Cyclin-dependent kinase 22.7.11.220.484
4fki09KCyclin-dependent kinase 22.7.11.220.484
1v1k3FPCyclin-dependent kinase 22.7.11.220.483
2vtrLZBCyclin-dependent kinase 22.7.11.220.483
3qu0X40Cyclin-dependent kinase 22.7.11.220.483
1ykr628Cyclin-dependent kinase 22.7.11.220.482
2a4lRRCCyclin-dependent kinase 22.7.11.220.480
3rk708ZCyclin-dependent kinase 22.7.11.220.479
3rm719ZCyclin-dependent kinase 22.7.11.220.478
3rpv26ZCyclin-dependent kinase 22.7.11.220.478
3qtxX43Cyclin-dependent kinase 22.7.11.220.476
2w06FRVCyclin-dependent kinase 22.7.11.220.475
2w1hL0FCyclin-dependent kinase 22.7.11.220.475
4fklCK2Cyclin-dependent kinase 22.7.11.220.474
3rjc06ZCyclin-dependent kinase 22.7.11.220.473
4fkg4CKCyclin-dependent kinase 22.7.11.220.473
1gii1PUCyclin-dependent kinase 22.7.11.220.472
1y91CT9Cyclin-dependent kinase 22.7.11.220.472
3rni21ZCyclin-dependent kinase 22.7.11.220.471
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.470
2xmyCDKCyclin-dependent kinase 22.7.11.220.470
3r7uX96Cyclin-dependent kinase 22.7.11.220.469
1w0xOLOCyclin-dependent kinase 22.7.11.220.468
3fz1B98Cyclin-dependent kinase 22.7.11.220.468
2b53D23Cyclin-dependent kinase 22.7.11.220.467
3qxoX65Cyclin-dependent kinase 22.7.11.220.464
1b38ATPCyclin-dependent kinase 22.7.11.220.463
1di8DTQCyclin-dependent kinase 22.7.11.220.463
3qtzX42Cyclin-dependent kinase 22.7.11.220.463
3s1h56ZCyclin-dependent kinase 22.7.11.220.463
2b52D42Cyclin-dependent kinase 22.7.11.220.462
3rak03ZCyclin-dependent kinase 22.7.11.220.462
3wblPDYCyclin-dependent kinase 22.7.11.220.461
2r3lSCWCyclin-dependent kinase 22.7.11.220.460
3ezvEZVCyclin-dependent kinase 22.7.11.220.460
3qtuX44Cyclin-dependent kinase 22.7.11.220.460
3raiX85Cyclin-dependent kinase 22.7.11.220.460
4fkv61KCyclin-dependent kinase 22.7.11.220.460
1p2a5BNCyclin-dependent kinase 22.7.11.220.459
2r3p3SCCyclin-dependent kinase 22.7.11.220.459
3sw418KCyclin-dependent kinase 22.7.11.220.459
1e1xNW1Cyclin-dependent kinase 22.7.11.220.458
2uznC96Cyclin-dependent kinase 22.7.11.220.458
3r8pZ46Cyclin-dependent kinase 22.7.11.220.457
1ke9LS5Cyclin-dependent kinase 22.7.11.220.456
2c6mDT5Cyclin-dependent kinase 22.7.11.220.456
3r73X87Cyclin-dependent kinase 22.7.11.220.456
4fkj11KCyclin-dependent kinase 22.7.11.220.455
3sqq99ZCyclin-dependent kinase 22.7.11.220.453
2r3iSCFCyclin-dependent kinase 22.7.11.220.451
2vv9IM9Cyclin-dependent kinase 22.7.11.220.451
1pxlCK4Cyclin-dependent kinase 22.7.11.220.450
1pxpCK8Cyclin-dependent kinase 22.7.11.220.450
2b55D31Cyclin-dependent kinase 22.7.11.220.450
2c6lDT4Cyclin-dependent kinase 22.7.11.220.450
1ckpPVBCyclin-dependent kinase 22.7.11.220.449
3sw719KCyclin-dependent kinase 22.7.11.220.448
4fko20KCyclin-dependent kinase 22.7.11.220.448
2c6iDT1Cyclin-dependent kinase 22.7.11.220.447
3rm618ZCyclin-dependent kinase 22.7.11.220.446
2w05FRTCyclin-dependent kinase 22.7.11.220.445
3qzhX69Cyclin-dependent kinase 22.7.11.220.445
3lfsA07Cyclin-dependent kinase 22.7.11.220.443
3qqhX0ACyclin-dependent kinase 22.7.11.220.442
3qxpX64Cyclin-dependent kinase 22.7.11.220.442
3rpo24ZCyclin-dependent kinase 22.7.11.220.442
4fks46KCyclin-dependent kinase 22.7.11.220.442