Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2a0cCK9Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2a0cCK9Cyclin-dependent kinase 22.7.11.221.000
4fklCK2Cyclin-dependent kinase 22.7.11.220.569
1oitHDTCyclin-dependent kinase 22.7.11.220.568
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.568
2c6o4SPCyclin-dependent kinase 22.7.11.220.563
3qzgX67Cyclin-dependent kinase 22.7.11.220.558
2btrU73Cyclin-dependent kinase 22.7.11.220.553
4fki09KCyclin-dependent kinase 22.7.11.220.552
3lfnA27Cyclin-dependent kinase 22.7.11.220.550
1w8cN69Cyclin-dependent kinase 22.7.11.220.546
3r8lZ30Cyclin-dependent kinase 22.7.11.220.541
2a4lRRCCyclin-dependent kinase 22.7.11.220.539
1ykr628Cyclin-dependent kinase 22.7.11.220.538
3lfqA28Cyclin-dependent kinase 22.7.11.220.533
3r1yX76Cyclin-dependent kinase 22.7.11.220.533
1pxlCK4Cyclin-dependent kinase 22.7.11.220.530
3r7yZ04Cyclin-dependent kinase 22.7.11.220.528
3r83Z14Cyclin-dependent kinase 22.7.11.220.526
2r3jSCJCyclin-dependent kinase 22.7.11.220.523
4ek610KCyclin-dependent kinase 22.7.11.220.523
1pxmCK5Cyclin-dependent kinase 22.7.11.220.521
4fkt48KCyclin-dependent kinase 22.7.11.220.519
3qwjX6ACyclin-dependent kinase 22.7.11.220.516
4ek816KCyclin-dependent kinase 22.7.11.220.516
3r8vZ62Cyclin-dependent kinase 22.7.11.220.513
1pxoCK7Cyclin-dependent kinase 22.7.11.220.512
2exmZIPCyclin-dependent kinase 22.7.11.220.506
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.506
3rpo24ZCyclin-dependent kinase 22.7.11.220.506
2b53D23Cyclin-dependent kinase 22.7.11.220.505
1ke5LS1Cyclin-dependent kinase 22.7.11.220.502
2uzoC62Cyclin-dependent kinase 22.7.11.220.502
2xmyCDKCyclin-dependent kinase 22.7.11.220.501
1g5sI17Cyclin-dependent kinase 22.7.11.220.499
4fkpLS5Cyclin-dependent kinase 22.7.11.220.498
4fkq42KCyclin-dependent kinase 22.7.11.220.497
3iggEFQCyclin-dependent kinase 22.7.11.220.494
3s2pPMUCyclin-dependent kinase 22.7.11.220.494
1y91CT9Cyclin-dependent kinase 22.7.11.220.493
1w0xOLOCyclin-dependent kinase 22.7.11.220.490
1oirHDYCyclin-dependent kinase 22.7.11.220.489
3s1h56ZCyclin-dependent kinase 22.7.11.220.489
3lfsA07Cyclin-dependent kinase 22.7.11.220.486
3qqlX03Cyclin-dependent kinase 22.7.11.220.486
4fkj11KCyclin-dependent kinase 22.7.11.220.486
2b55D31Cyclin-dependent kinase 22.7.11.220.483
3r7uX96Cyclin-dependent kinase 22.7.11.220.483
3rni21ZCyclin-dependent kinase 22.7.11.220.482
1gii1PUCyclin-dependent kinase 22.7.11.220.481
3qxoX65Cyclin-dependent kinase 22.7.11.220.479
2r3p3SCCyclin-dependent kinase 22.7.11.220.476
2vtsLZCCyclin-dependent kinase 22.7.11.220.475
1v1k3FPCyclin-dependent kinase 22.7.11.220.474
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.474
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.474
3qu0X40Cyclin-dependent kinase 22.7.11.220.474
2r3mSCXCyclin-dependent kinase 22.7.11.220.473
3r7vZ02Cyclin-dependent kinase 22.7.11.220.473
3rak03ZCyclin-dependent kinase 22.7.11.220.473
1ke7LS3Cyclin-dependent kinase 22.7.11.220.472
4acm7YGCyclin-dependent kinase 22.7.11.220.472
1b38ATPCyclin-dependent kinase 22.7.11.220.471
2ds11CDCyclin-dependent kinase 22.7.11.220.471
3rjc06ZCyclin-dependent kinase 22.7.11.220.471
4fkg4CKCyclin-dependent kinase 22.7.11.220.471
3rk708ZCyclin-dependent kinase 22.7.11.220.469
4fks46KCyclin-dependent kinase 22.7.11.220.468
1y8yCT7Cyclin-dependent kinase 22.7.11.220.466
4fkv61KCyclin-dependent kinase 22.7.11.220.465
1e1xNW1Cyclin-dependent kinase 22.7.11.220.464
2uznC96Cyclin-dependent kinase 22.7.11.220.464
2w06FRVCyclin-dependent kinase 22.7.11.220.464
3qqhX0ACyclin-dependent kinase 22.7.11.220.464
2c6lDT4Cyclin-dependent kinase 22.7.11.220.463
3rkb12ZCyclin-dependent kinase 22.7.11.220.463
2c6kDT2Cyclin-dependent kinase 22.7.11.220.461
3rahO1ZCyclin-dependent kinase 22.7.11.220.461
1hckATPCyclin-dependent kinase 22.7.11.220.460
2btsU32Cyclin-dependent kinase 22.7.11.220.460
2r3kSCQCyclin-dependent kinase 22.7.11.220.460
2b52D42Cyclin-dependent kinase 22.7.11.220.459
2r3lSCWCyclin-dependent kinase 22.7.11.220.459
3sw418KCyclin-dependent kinase 22.7.11.220.458
3qtuX44Cyclin-dependent kinase 22.7.11.220.456
3rk909ZCyclin-dependent kinase 22.7.11.220.456
3rpv26ZCyclin-dependent kinase 22.7.11.220.454
2duv371Cyclin-dependent kinase 22.7.11.220.452
3r71X86Cyclin-dependent kinase 22.7.11.220.452
3ezvEZVCyclin-dependent kinase 22.7.11.220.451
2vtrLZBCyclin-dependent kinase 22.7.11.220.450
1ke6LS2Cyclin-dependent kinase 22.7.11.220.448
1pxpCK8Cyclin-dependent kinase 22.7.11.220.447
2w1hL0FCyclin-dependent kinase 22.7.11.220.446
3sw719KCyclin-dependent kinase 22.7.11.220.446
1aq1STUCyclin-dependent kinase 22.7.11.220.444
3rm618ZCyclin-dependent kinase 22.7.11.220.444
3qtrX36Cyclin-dependent kinase 22.7.11.220.441
3r9dX6BCyclin-dependent kinase 22.7.11.220.441
3rmf20ZCyclin-dependent kinase 22.7.11.220.440