Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5aku29FTankyrase-22.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5aku29FTankyrase-22.4.2.301.000
4hlk431Tankyrase-22.4.2.300.881
4buiW2ETankyrase-22.4.2.300.839
4but31FTankyrase-22.4.2.300.819
4buuF38Tankyrase-22.4.2.300.803
4l0s1UZTankyrase-22.4.2.300.779
4bufF36Tankyrase-22.4.2.300.762
4bu908CTankyrase-22.4.2.300.743
4kzl20DTankyrase-22.4.2.300.705
4l2f1V3Tankyrase-22.4.2.300.703
4hkiFLNTankyrase-22.4.2.300.683
4l10A63Tankyrase-22.4.2.300.680
4l0v1V1Tankyrase-22.4.2.300.675
4avwG18Tankyrase-22.4.2.300.674
3kr8XAVTankyrase-22.4.2.300.660
4hlg20BTankyrase-22.4.2.300.659
4hkkAGITankyrase-22.4.2.300.656
4l321VFTankyrase-22.4.2.300.656
4l341VGTankyrase-22.4.2.300.655
4bueJQFTankyrase-22.4.2.300.654
4l2g1V4Tankyrase-22.4.2.300.650
4l31F08Tankyrase-22.4.2.300.649
4l2k1V8Tankyrase-22.4.2.300.647
4l33F70Tankyrase-22.4.2.300.641
4bud29FTankyrase-22.4.2.300.640
4l0i1UWTankyrase-22.4.2.300.639
4l0t1V0Tankyrase-22.4.2.300.639
4buxF35Tankyrase-22.4.2.300.630
4hlf15ZTankyrase-22.4.2.300.630
4bus32FTankyrase-22.4.2.300.624
4hlh20DTankyrase-22.4.2.300.624
4kzuA73Tankyrase-22.4.2.300.623
4hknLU2Tankyrase-22.4.2.300.621
4j22AJ7Tankyrase-22.4.2.300.618
4hlm16STankyrase-22.4.2.300.614
4j21AJ6Tankyrase-22.4.2.300.613
4hl515WTankyrase-22.4.2.300.611
4iueAJ4Tankyrase-22.4.2.300.605
4hmhF94Tankyrase-22.4.2.300.589
4buv16ITankyrase-22.4.2.300.584
3p0pNNFTankyrase-22.4.2.300.582
4buwF33Tankyrase-22.4.2.300.574
4bs4A64Tankyrase-22.4.2.300.560
4krs1SXTankyrase-12.4.2.300.546
4tkg09LTankyrase-22.4.2.300.537
3u9y09LTankyrase-22.4.2.300.533
4pnrG18Tankyrase-22.4.2.300.531
4bjbP34Tankyrase-22.4.2.300.526
4bj9UHBTankyrase-22.4.2.300.512
4l091URTankyrase-22.4.2.300.504
4msk2C8Tankyrase-12.4.2.300.503
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.496
4j3lAJ5Tankyrase-22.4.2.300.490
4j3mAJ8Tankyrase-22.4.2.300.488
4pnmNU1Tankyrase-22.4.2.300.486
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.476
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.461
4tjy3GNTankyrase-22.4.2.300.461
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.457
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.457
1xk9P34Exotoxin A2.4.2.360.450
4avuLDRTankyrase-22.4.2.300.450
3rsv3RSBeta-secretase 13.4.23.460.449
4u140HKMuscarinic acetylcholine receptor M3/0.448
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.447
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.447
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.446
3zkyWT4Isopenicillin N synthase1.21.3.10.445
1obnASVIsopenicillin N synthase1.21.3.10.444
3qe2FADNADPH--cytochrome P450 reductase/0.444
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.444
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.442
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.441
5c1mCLRMu-type opioid receptor/0.441
3b82NADExotoxin A2.4.2.360.440