Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4lrjANPUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4lrjANPUncharacterized protein/1.000
5dnrATPAurora kinase A2.7.11.10.496
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.495
4deeADPAurora kinase A2.7.11.10.484
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.483
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.480
3cgfJNFMitogen-activated protein kinase 102.7.11.240.479
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.477
1ig1ANPDeath-associated protein kinase 12.7.11.10.476
5l8lADPAurora kinase A2.7.11.10.476
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.475
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.474
3i60E86Mitogen-activated protein kinase 12.7.11.240.473
3orpAGSSerine/threonine protein kinase/0.473
3gu7ADPDeath-associated protein kinase 12.7.11.10.471
2ijmATPFocal adhesion kinase 12.7.10.20.470
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.470
3efwAK8Aurora kinase A2.7.11.10.468
3ortAGSSerine/threonine protein kinase/0.467
5dosATPAurora kinase A2.7.11.10.467
4qnyANPMitogen activated protein kinase, putative/0.466
1i44ACPInsulin receptor2.7.10.10.464
4fvqATPTyrosine-protein kinase JAK2/0.464
4o0uADNAurora kinase A2.7.11.10.464
4o1pANPRibonuclease L/0.464
1pmn984Mitogen-activated protein kinase 102.7.11.240.462
4qmlANPSerine/threonine-protein kinase 242.7.11.10.461
2w4jADPDeath-associated protein kinase 12.7.11.10.458
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.458
4btjATPTau-tubulin kinase 12.7.11.10.457
4eooATPCyclin-dependent kinase 22.7.11.220.457
4s33ANPMitogen-activated protein kinase 12.7.11.240.457
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.456
2henADPEphrin type-B receptor 22.7.10.10.455
4ix5ANPUncharacterized protein/0.454
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.453
3kvxFMYMitogen-activated protein kinase 102.7.11.240.453
4btjADPTau-tubulin kinase 12.7.11.10.453
4i3zADPCyclin-dependent kinase 22.7.11.220.453
4lfiGNPCasein kinase II subunit alpha2.7.11.10.453
3c4wATPRhodopsin kinase/0.452
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.451
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.450
4c3pACPAurora kinase A2.7.11.10.450
1dawANPCasein kinase II subunit alpha2.7.11.10.449
2cciATPCyclin-dependent kinase 22.7.11.220.449
2j0lANPFocal adhesion kinase 12.7.10.20.449
3t8oATPRhodopsin kinase/0.449
1rkxNADCDP-D-glucose-4,6-dehydratase/0.448
4hge15VTyrosine-protein kinase JAK2/0.448
4y95746Tyrosine-protein kinase/0.448
3bu5ATPInsulin receptor2.7.10.10.447
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.447
4k2rANPTyrosine-protein kinase ZAP-702.7.10.20.447
5dt3ATPAurora kinase A2.7.11.10.447
1jnkANPMitogen-activated protein kinase 102.7.11.240.446
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.446
4jbpYPHAurora kinase A2.7.11.10.446
2qoqANPEphrin type-A receptor 32.7.10.10.445
2xs0ANPMitogen-activated protein kinase 82.7.11.240.445
2ozoANPTyrosine-protein kinase ZAP-702.7.10.20.444
3wfjNAD2-dehydropantoate 2-reductase/0.444
4jboWPHAurora kinase A2.7.11.10.444
2wqeADPAurora kinase A2.7.11.10.443
3orkAGSSerine/threonine protein kinase/0.443
3zxtACPDeath-associated protein kinase 12.7.11.10.443
4l9i8PRRhodopsin kinase/0.443
1dayGNPCasein kinase II subunit alpha2.7.11.10.442
1qmzATPCyclin-dependent kinase 22.7.11.220.442
2w1fL0FAurora kinase A2.7.11.10.442
4j95ACPFibroblast growth factor receptor 2/0.442
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.442
1w8cN69Cyclin-dependent kinase 22.7.11.220.441
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.441
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.441
2dcnADP2-keto-3-deoxy-gluconate kinase/0.441
3c4zADPRhodopsin kinase/0.440
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.440
4xlvACPInsulin receptor2.7.10.10.440