Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/1.000
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.749
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.719
3ox279XRibosyldihydronicotinamide dehydrogenase [quinone]/0.667
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.652
3owxXRARibosyldihydronicotinamide dehydrogenase [quinone]/0.651
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.622
4fgj1PQRibosyldihydronicotinamide dehydrogenase [quinone]/0.619
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.616
3nhrRZWRibosyldihydronicotinamide dehydrogenase [quinone]/0.607
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.606
1xi2CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.605
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.591
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.584
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.582
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.577
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.575
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.566
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.562
3gamMXXRibosyldihydronicotinamide dehydrogenase [quinone]/0.559
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.558
3nhlYTRRibosyldihydronicotinamide dehydrogenase [quinone]/0.557
4qohSTLRibosyldihydronicotinamide dehydrogenase [quinone]/0.550
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.539
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.538
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.531
1sg0STLRibosyldihydronicotinamide dehydrogenase [quinone]/0.530
3nhuM42Ribosyldihydronicotinamide dehydrogenase [quinone]/0.517
4bftZVTPantothenate kinase2.7.1.330.459
4bfxZVXPantothenate kinase2.7.1.330.459
1amoFMNNADPH--cytochrome P450 reductase/0.455
4bfwZVWPantothenate kinase2.7.1.330.455
1pqc444Oxysterols receptor LXR-beta/0.451
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
1s7gNADNAD-dependent protein deacylase 2/0.448
3ezpB3NHistone deacetylase 83.5.1.980.448
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.447
1qiqACCIsopenicillin N synthase1.21.3.10.447
2geuCOKPantothenate kinase2.7.1.330.447
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.445
1xddAAYIntegrin alpha-L/0.444
4qa0SHHHistone deacetylase 83.5.1.980.444
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.443
1blzACVIsopenicillin N synthase1.21.3.10.442
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1pl6572Sorbitol dehydrogenase1.1.1.140.442
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.442
1x8lOXRRetinol dehydratase/0.441
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3g5mFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
4q0kGA3Phytohormone-binding protein/0.441
2rqfJH3Hemolymph juvenile hormone binding protein/0.440
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.440