scPDB - Distribution of Binding site Similarity values of 3for entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3for	ZNP	Thermolysin	3.4.24.27

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3for	ZNP	Thermolysin	3.4.24.27	1.000
4h57	0PJ	Thermolysin	3.4.24.27	0.728
3f28	S7B	Thermolysin	3.4.24.27	0.657
2tmn	0FA	Thermolysin	3.4.24.27	0.640
4tln	LNO	Thermolysin	3.4.24.27	0.639
3fgd	BYA	Thermolysin	3.4.24.27	0.628
1qf2	TI3	Thermolysin	3.4.24.27	0.623
3t8d	UBV	Thermolysin	3.4.24.27	0.619
6tmn	0PI	Thermolysin	3.4.24.27	0.619
3f2p	S3B	Thermolysin	3.4.24.27	0.618
4tmn	0PK	Thermolysin	3.4.24.27	0.600
4d9w	X32	Thermolysin	3.4.24.27	0.594
3t74	UBY	Thermolysin	3.4.24.27	0.592
3t8h	UBS	Thermolysin	3.4.24.27	0.592
3t8c	UBW	Thermolysin	3.4.24.27	0.590
3t87	UBZ	Thermolysin	3.4.24.27	0.582
4b52	RDF	Bacillolysin	/	0.518
4ara	C56	Acetylcholinesterase	3.1.1.7	0.491
3bmo	NAP	Pteridine reductase	/	0.478
2gr1	FAD	Ferredoxin reductase	/	0.473
1q84	TZ4	Acetylcholinesterase	3.1.1.7	0.470
1g4k	HQQ	Stromelysin-1	3.4.24.17	0.469
3uxv	GUN	NADPH-dependent 7-cyano-7-deazaguanine reductase	/	0.468
2j83	BAT	Ulilysin	3.4.24	0.467
1yqy	915	Lethal factor	3.4.24.83	0.466
1szg	FNS	Cytochrome b2, mitochondrial	1.1.2.3	0.464
2x95	X95	Angiotensin-converting enzyme	3.4.15.1	0.463
1eio	GCH	Gastrotropin	/	0.462
2fs4	PZ1	Renin	3.4.23.15	0.462
2vat	COA	Acetyl-CoA--deacetylcephalosporin C acetyltransferase	2.3.1.175	0.462
4ca5	3EF	Angiotensin-converting enzyme	3.2.1	0.462
2bjf	DXC	Choloylglycine hydrolase	3.5.1.24	0.461
3tjz	GNP	ADP-ribosylation factor 1	/	0.461
2wvl	GDD	Mannosyl-3-phosphogylcerate synthase	/	0.459
1w7h	3IP	Mitogen-activated protein kinase 14	/	0.455
2ibw	COA	Acetyl-CoA acetyltransferase, mitochondrial	2.3.1.9	0.455
4fry	NAD	Putative signal-transduction protein with CBS domains	/	0.455
3q43	D66	M1 family aminopeptidase	3.4.11	0.454
1l2o	ADP	Myosin heavy chain, striated muscle	/	0.453
2aba	STR	Pentaerythritol tetranitrate reductase	/	0.453
2b37	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.453
2i4z	DRH	Peroxisome proliferator-activated receptor gamma	/	0.453
5f8e	SAH	Possible transcriptional regulatory protein	/	0.453
1dnc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.452
2c2a	ADP	Sensor histidine kinase	/	0.452
2uxo	TAC	HTH-type transcriptional regulator TtgR	/	0.452
3h3q	H13	Collagen type IV alpha-3-binding protein	/	0.452
3fv4	1U4	Thermolysin	3.4.24.27	0.451
3ooi	SAM	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	2.1.1.43	0.451
1jwt	BLI	Prothrombin	3.4.21.5	0.450
2ea4	F79	Methionine aminopeptidase 2	/	0.450
2oap	ANP	Type II secretion system protein (GspE-2)	/	0.450
2q8s	L92	Peroxisome proliferator-activated receptor gamma	/	0.450
3e34	ED1	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	/	0.450
3e34	ED1	Protein farnesyltransferase subunit beta	2.5.1.58	0.450
3f3s	NAD	Lambda-crystallin homolog	/	0.450
1o86	LPR	Angiotensin-converting enzyme	3.2.1	0.449
2h21	SAM	Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic	2.1.1.127	0.449
3p2e	SAH	16S rRNA (adenine(1408)-N(1))-methyltransferase	2.1.1.180	0.448
4ca7	3EF	Angiotensin-converting enzyme	3.4.15.1	0.448
4dja	FAD	(6-4) photolyase	/	0.448
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.447
2x92	X92	Angiotensin-converting enzyme	3.4.15.1	0.447
3to0	FMN	Iodotyrosine deiodinase 1	1.21.1.1	0.447
3uyl	TYD	Probable NDP-rhamnosyltransferase	/	0.447
4bft	ZVT	Pantothenate kinase	2.7.1.33	0.447
2c31	TZD	Oxalyl-CoA decarboxylase	4.1.1.8	0.446
2ejv	NAD	L-threonine 3-dehydrogenase	/	0.446
3qd4	3Q6	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.446
4b7z	Q4Q	Acetylcholinesterase	3.1.1.7	0.446
4ipw	1G7	Mycocyclosin synthase	1.14.21.9	0.446
1xh9	R69	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.445
2gyw	OBI	Acetylcholinesterase	3.1.1.7	0.445
4b66	NAP	L-ornithine N(5)-monooxygenase	/	0.445
4zr5	RDF	Neprilysin	/	0.445
1me6	IVS	Plasmepsin-2	3.4.23.39	0.444
4iql	FMN	Enoyl-(Acyl-carrier-protein) reductase II	/	0.444
2g26	3LG	Renin	3.4.23.15	0.443
2uzu	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.443
2w3b	NDP	Dihydrofolate reductase	1.5.1.3	0.443
2ylr	NAP	Phenylacetone monooxygenase	1.14.13.92	0.443
3hyg	099	A disintegrin and metalloproteinase with thrombospondin motifs 5	3.4.24	0.443
3v2u	ATP	Protein GAL3	/	0.443
4cf6	CBD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.443
4dpt	AGS	Mevalonate diphosphate decarboxylase	/	0.443
5c93	ACP	Two-component system histidine protein kinase	/	0.443
1e3e	NAI	Alcohol dehydrogenase 4	1.1.1.1	0.442
1h22	E10	Acetylcholinesterase	3.1.1.7	0.442
1ps9	MDE	2,4-dienoyl-CoA reductase	1.3.1.34	0.442
2f7x	4EA	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.442
2gtb	AZP	Orf1ab polyprotein	/	0.442
2p9g	NAI	D-3-phosphoglycerate dehydrogenase	1.1.1.95	0.442
3ohh	3HH	Beta-secretase 1	3.4.23.46	0.442
1r4l	XX5	Angiotensin-converting enzyme 2	3.4.17.23	0.441
3nxq	RX4	Angiotensin-converting enzyme	3.2.1	0.441
4b14	4XB	Glycylpeptide N-tetradecanoyltransferase	/	0.441
4bxk	1IU	Angiotensin-converting enzyme	3.2.1	0.441
4gh5	NAD	Short-chain dehydrogenase/reductase SDR	/	0.441
2c1b	CQP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.440
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.440
4lcj	NAD	C-terminal-binding protein 2	/	0.440