scPDB - Distribution of Binding site Similarity values of 3elm entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3elm	24F	Collagenase 3	3.4.24

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3elm	24F	Collagenase 3	3.4.24	1.000
2bu9	HFV	Isopenicillin N synthase	1.21.3.1	0.488
4a32	2CD	Glycylpeptide N-tetradecanoyltransferase	/	0.478
4bfs	ZVS	Pantothenate kinase	2.7.1.33	0.477
4kqq	VPP	Peptidoglycan D,D-transpeptidase FtsI	/	0.475
1osv	CHC	Bile acid receptor	/	0.473
3d5q	T30	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.473
2uag	UMA	UDP-N-acetylmuramoylalanine--D-glutamate ligase	6.3.2.9	0.472
3b9l	AZZ	Serum albumin	/	0.469
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.468
1xzq	FON	tRNA modification GTPase MnmE	3.6.5	0.466
3dds	26B	Glycogen phosphorylase, liver form	2.4.1.1	0.466
3owu	EQU	Steroid Delta-isomerase	5.3.3.1	0.465
3c0i	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.464
4uyg	73B	Bromodomain-containing protein 2	/	0.462
1zg3	2HI	Isoflavone 4'-O-methyltransferase	/	0.460
1h50	FMN	Pentaerythritol tetranitrate reductase	/	0.459
1ry0	PG2	Aldo-keto reductase family 1 member C3	/	0.458
3g5q	FAD	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	/	0.458
1h51	FMN	Pentaerythritol tetranitrate reductase	/	0.457
3nr4	PYV	Abscisic acid receptor PYL2	/	0.457
4h6p	FMN	Chromate reductase	/	0.457
4jq3	ZOM	Aldo-keto reductase family 1 member C2	/	0.457
3br3	ET	HTH-type transcriptional regulator QacR	/	0.456
3nj0	PYV	Abscisic acid receptor PYL2	/	0.456
4mry	CEI	Obelin	/	0.456
2vcm	M11	Isopenicillin N synthase	1.21.3.1	0.455
2xvv	9DN	Serum albumin	/	0.455
3qiy	QI1	Botulinum neurotoxin type A	3.4.24.69	0.455
5c1m	CLR	Mu-type opioid receptor	/	0.455
1fml	RTL	Retinol dehydratase	/	0.454
1lkd	BP6	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39	0.454
1ndz	FR5	Adenosine deaminase	3.5.4.4	0.454
2xvi	FAD	Putative flavin-containing monooxygenase	/	0.454
4cvm	ANP	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	/	0.454
4kw5	1W6	Decaprenylphosphoryl-beta-D-ribose oxidase	/	0.454
2j3q	TFL	Acetylcholinesterase	3.1.1.7	0.452
2jb4	A14	Isopenicillin N synthase	1.21.3.1	0.452
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.452
3dh7	FMN	Isopentenyl-diphosphate delta-isomerase	/	0.452
3zho	FMN	NAD(P)H dehydrogenase (quinone)	/	0.452
1pq9	44B	Oxysterols receptor LXR-beta	/	0.451
1qyw	5SD	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.451
2hxz	H7J	Cathepsin S	3.4.22.27	0.451
2zsd	COA	Pantothenate kinase	2.7.1.33	0.451
3zoi	M2W	Isopenicillin N synthase	1.21.3.1	0.451
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.451
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.450
1ot7	IU5	Bile acid receptor	/	0.450
1bk0	ACV	Isopenicillin N synthase	1.21.3.1	0.449
1tbb	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.449
3p62	FMN	Pentaerythritol tetranitrate reductase	/	0.449
4a30	QMI	Glycylpeptide N-tetradecanoyltransferase	/	0.449
4g8z	TOP	Dihydrofolate reductase	1.5.1.3	0.449
1rd4	L08	Integrin alpha-L	/	0.448
2xlr	FAD	Putative flavin-containing monooxygenase	/	0.448
2xvw	9NR	Serum albumin	/	0.448
3hxe	BD8	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.448
4psb	GA3	Cytokinin-specific binding protein	/	0.448
1kzj	CB3	Thymidylate synthase	/	0.447
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.447
1odn	APV	Isopenicillin N synthase	1.21.3.1	0.447
1qyx	ASD	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.447
3pz2	3PZ	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.447
1mrq	STR	Aldo-keto reductase family 1 member C1	/	0.446
1ot7	CHC	Bile acid receptor	/	0.446
1uzw	CDH	Isopenicillin N synthase	1.21.3.1	0.446
2bjs	ACV	Isopenicillin N synthase	1.21.3.1	0.446
2jj2	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.446
2v58	LZJ	Biotin carboxylase	6.3.4.14	0.446
2zba	ZBA	Trichothecene 3-O-acetyltransferase	/	0.446
4bfw	ZVW	Pantothenate kinase	2.7.1.33	0.446
4jq4	IMN	Aldo-keto reductase family 1 member C2	/	0.446
4rup	H97	Vitamin D3 receptor A	/	0.446
4u0s	ADP	Adenosine monophosphate-protein transferase FICD	2.7.7.n1	0.446
2b03	TUD	Phospholipase A2, major isoenzyme	3.1.1.4	0.445
2e98	B29	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.445
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.445
2jh6	894	Prothrombin	3.4.21.5	0.445
3c0g	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.445
4mqt	2CU	Muscarinic acetylcholine receptor M2	/	0.445
1qjf	ACS	Isopenicillin N synthase	1.21.3.1	0.444
1sd2	MTH	S-methyl-5'-thioadenosine phosphorylase	/	0.444
2o1s	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.444
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.444
3h18	PMS	Esterase/lipase	/	0.444
4ijr	NDP	D-arabinose dehydrogenase [NAD(P)+] heavy chain	1.1.1.117	0.444
1y2k	7DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.443
2a5c	8DA	Avidin	/	0.443
3cic	316	Beta-secretase 1	3.4.23.46	0.443
3ho2	N32	3-oxoacyl-[acyl-carrier-protein] synthase 2	2.3.1.179	0.443
1axw	MTX	Thymidylate synthase	/	0.442
1crb	RTL	Retinol-binding protein 1	/	0.442
1mp0	NAD	Alcohol dehydrogenase class-3	1.1.1.1	0.442
2jbs	FMN	p-hydroxyphenylacetate 3-hydroxylase, oxygenase component	/	0.442
2xi4	AFT	Acetylcholinesterase	3.1.1.7	0.442
2xve	FAD	Putative flavin-containing monooxygenase	/	0.442
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.442
3q2j	CKI	Aminoglycoside 3'-phosphotransferase	2.7.1.95	0.442
3to3	ATP	Petrobactin biosynthesis protein AsbB	/	0.442
4kby	C2E	Stimulator of interferon genes protein	/	0.442
4v12	POG	MaoC like domain protein	/	0.442
1kqu	BR4	Phospholipase A2, membrane associated	/	0.441
2j3j	HC4	NADPH-dependent oxidoreductase 2-alkenal reductase	1.3.1.74	0.441
2v59	LZK	Biotin carboxylase	6.3.4.14	0.441
3dyn	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.441
3uyk	0CX	Probable NDP-rhamnosyltransferase	/	0.441
4qjq	OTR	Lactoperoxidase	/	0.441
4zzi	1NS	NAD-dependent protein deacetylase sirtuin-1	3.5.1	0.441
1zrz	BI1	Protein kinase C iota type	2.7.11.13	0.440
2jfz	003	Glutamate racemase	/	0.440
2rd2	QSI	Glutamine--tRNA ligase	6.1.1.18	0.440
3af1	GDP	Pantothenate kinase	2.7.1.33	0.440
3c1t	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.440
3dey	DHT	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.440
3klm	DHT	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.440
3maa	FKP	Adenylate cyclase type 2	/	0.440
3maa	FKP	Adenylate cyclase type 5	/	0.440
3oqk	S52	Renin	3.4.23.15	0.440
3p8j	FMN	Pentaerythritol tetranitrate reductase	/	0.440
4f1l	0RY	Poly [ADP-ribose] polymerase 14	2.4.2.30	0.440
5hs1	VOR	Lanosterol 14-alpha demethylase	/	0.440