Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3dghFADThioredoxin reductase 1, mitochondrial1.8.1.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3dghFADThioredoxin reductase 1, mitochondrial1.8.1.91.000
2nvkFADThioredoxin reductase 1, mitochondrial1.8.1.90.623
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.610
3dh9FADThioredoxin reductase 1, mitochondrial1.8.1.90.594
3qfbFADThioredoxin reductase 1, cytoplasmic1.8.1.90.593
2cfyFADThioredoxin reductase 1, cytoplasmic1.8.1.90.575
2zzcFADThioredoxin reductase 1, cytoplasmic1.8.1.90.575
4kprFADThioredoxin reductase 1, cytoplasmic1.8.1.90.570
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.554
1h6vFADThioredoxin reductase 1, cytoplasmic1.8.1.90.551
3dgzFADThioredoxin reductase 2, mitochondrial1.8.1.90.546
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.542
1gerFADGlutathione reductase1.8.1.70.538
3sqpFADGlutathione reductase, mitochondrial1.8.1.70.537
1geuFADGlutathione reductase1.8.1.70.532
2r9zFADGlutathione amide reductase/0.521
1gsnFADGlutathione reductase, mitochondrial1.8.1.70.520
1greFADGlutathione reductase, mitochondrial1.8.1.70.519
2rabFADGlutathione amide reductase/0.519
1grhFADGlutathione reductase, mitochondrial1.8.1.70.512
1onfFADGlutathione reductase1.8.1.70.512
3dk9FADGlutathione reductase, mitochondrial1.8.1.70.512
4gr1FADGlutathione reductase, mitochondrial1.8.1.70.512
1getFADGlutathione reductase1.8.1.70.510
1grgFADGlutathione reductase, mitochondrial1.8.1.70.506
1febFADTrypanothione reductase1.8.1.120.505
3dk8FADGlutathione reductase, mitochondrial1.8.1.70.505
4j56FADThioredoxin reductase 21.8.1.90.503
1bwcFADGlutathione reductase, mitochondrial1.8.1.70.502
2v6oFADThioredoxin glutathione reductase/0.498
3dk4FADGlutathione reductase, mitochondrial1.8.1.70.496
1zk7FADMercuric reductase1.16.1.10.485
3djgFADGlutathione reductase, mitochondrial1.8.1.70.484
1lpfFADDihydrolipoyl dehydrogenase1.8.1.40.483
3ladFADDihydrolipoyl dehydrogenase/0.482
1h7wFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.479
1feaFADTrypanothione reductase1.8.1.120.475
4eqsFADCoenzyme A disulfide reductase/0.475
4nevFADTrypanothione reductase/0.473
1grbFADGlutathione reductase, mitochondrial1.8.1.70.467
1graFADGlutathione reductase, mitochondrial1.8.1.70.465
1tdeFADThioredoxin reductase1.8.1.90.465
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.463
1yqzFADCoenzyme A disulfide reductase/0.462
1bzlFADTrypanothione reductase1.8.1.120.461
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.459
1zx9FADMercuric reductase1.16.1.10.456
3ic9FADPutative dihydrolipoamide dehydrogenase/0.456
4jq9FADDihydrolipoyl dehydrogenase/0.456
1zmdFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.455
4fx9FADCoenzyme A disulfide reductase1.8.1.140.452
1gteFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.451
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.447
2eq7FADDihydrolipoyl dehydrogenase/0.446
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.445
1tdfFADThioredoxin reductase1.8.1.90.444
3cgdFADCoenzyme A disulfide reductase/0.442
2vnaNAPProstaglandin reductase 21.3.1.480.441
2yquFADDihydrolipoyl dehydrogenase/0.440
3grsFADGlutathione reductase, mitochondrial1.8.1.70.440