Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2z0ySAMRibosomal RNA small subunit methyltransferase E

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2z0ySAMRibosomal RNA small subunit methyltransferase E/1.000
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.707
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
3hz5Z64Heat shock protein HSP 90-alpha/0.459
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
4g7gVFVLanosterol 14-alpha-demethylase/0.457
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
4jx1CAHCamphor 5-monooxygenase1.14.15.10.456
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.454
3fwiCAMCamphor 5-monooxygenase1.14.15.10.453
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.452
4g3jVNTLanosterol 14-alpha-demethylase/0.451
1k6cMK1Gag-Pol polyprotein3.4.23.160.450
3gggNADPrephenate dehydrogenase/0.450
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1xddAAYIntegrin alpha-L/0.449
3zuyTCHTransporter/0.449
4y8wSTRSteroid 21-hydroxylase/0.449
5idwNAPShort-chain dehydrogenase/reductase SDR/0.449
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.448
3g5hYTTMycocyclosin synthase1.14.21.90.448
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.448
2a1nCAMCamphor 5-monooxygenase1.14.15.10.447
1dz6CAMCamphor 5-monooxygenase1.14.15.10.446
1eupASD6-deoxyerythronolide B hydroxylase/0.446
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
3fwjCAMCamphor 5-monooxygenase1.14.15.10.446
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.446
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.445
1g6kNADGlucose 1-dehydrogenase1.1.1.470.444
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.443
4ejvLCLTranscriptional regulator TcaR/0.443
1cjtFOKAdenylate cyclase type 2/0.442
1cjtFOKAdenylate cyclase type 5/0.442
2om9AJAPeroxisome proliferator-activated receptor gamma/0.441
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.441
4ambDUDPutative glycosyl transferase/0.441
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.440
3cppCAMCamphor 5-monooxygenase1.14.15.10.440
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440