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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.634
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.614
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.603
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.601
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.596
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.590
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.570
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.569
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.568
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.550
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.539
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.537
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.521
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.518
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
1jklANPDeath-associated protein kinase 12.7.11.10.492
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
4otiMI1Serine/threonine-protein kinase N1/0.485
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.483
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.475
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.474
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.471
3dfcANPDeath-associated protein kinase 12.7.11.10.470
3gu6ADPDeath-associated protein kinase 12.7.11.10.469
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.469
5av2KMPDeath-associated protein kinase 12.7.11.10.469
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.468
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.464
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.462
2y9qANPMitogen-activated protein kinase 12.7.11.240.461
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.461
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.461
2ijmADPFocal adhesion kinase 12.7.10.20.460
5auvAGIDeath-associated protein kinase 12.7.11.10.456
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.455
5av3KMPDeath-associated protein kinase 12.7.11.10.454
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.452
4ic7ANPMitogen-activated protein kinase 72.7.11.240.452
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.451
4qnyANPMitogen activated protein kinase, putative/0.451
3gu7ADPDeath-associated protein kinase 12.7.11.10.448
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.447
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.446
3w2sW2REpidermal growth factor receptor2.7.10.10.446
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.445
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3nynSGVG protein-coupled receptor kinase 62.7.11.160.445
4j95ACPFibroblast growth factor receptor 2/0.445
2ojj82AMitogen-activated protein kinase 12.7.11.240.443
5auzGENDeath-associated protein kinase 12.7.11.10.442
1wvxBD4Death-associated protein kinase 12.7.11.10.441
2ckeIQUDeath-associated protein kinase 2/0.441
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.441
1finATPCyclin-dependent kinase 22.7.11.220.440
3bhy7CPDeath-associated protein kinase 3/0.440
4j99ACPFibroblast growth factor receptor 2/0.440