Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1zdfUPGGlycogenin-12.4.1.186

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1zdfUPGGlycogenin-12.4.1.1861.000
1zdgUPGGlycogenin-12.4.1.1860.609
3rmwUPGGlycogenin-12.4.1.1860.542
3v0p4GWHisto-blood group ABO system transferase/0.516
2e1zB4PPropionate kinase/0.502
4djhJDCKappa-type opioid receptor/0.500
5c3aURMHisto-blood group ABO system transferase/0.496
3t7oUPGGlycogenin-12.4.1.1860.493
1g93UPGN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.492
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.486
5c1lGDUHisto-blood group ABO system transferase/0.477
1i75NOJCyclomaltodextrin glucanotransferase2.4.1.190.473
3v0o4GWHisto-blood group ABO system transferase/0.472
4e5h0N8Polymerase acidic protein/0.469
1qwjNCCN-acylneuraminate cytidylyltransferase2.7.7.430.468
2gevCOKPantothenate kinase2.7.1.330.467
5c3bURMHisto-blood group ABO system transferase/0.467
2bf4FADNADPH--cytochrome P450 reductase/0.466
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.465
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.464
3dqrJI2Nitric oxide synthase, brain1.14.13.390.464
3iocA5DPantothenate synthetase6.3.2.10.464
2r0cFADPutative FAD-monooxygenase/0.463
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.460
3tm4SAMUncharacterized protein/0.460
5c48URMHisto-blood group ABO system transferase/0.460
1u1gBBBUridine phosphorylase2.4.2.30.459
2cduFADNADH oxidase/0.459
3hl0NADMaleylacetate reductase/0.459
3nlw3XFNitric oxide synthase, brain1.14.13.390.456
3q43D66M1 family aminopeptidase3.4.110.456
5c47URMHisto-blood group ABO system transferase/0.456
1ja0FMNNADPH--cytochrome P450 reductase/0.455
4e5lDBHPolymerase acidic protein/0.454
2xviFADPutative flavin-containing monooxygenase/0.453
1rfqLARActin, alpha skeletal muscle/0.452
3nnz59WNitric oxide synthase, brain1.14.13.390.452
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.451
1knrFADL-aspartate oxidase1.4.3.160.451
3apwDP0Alpha-1-acid glycoprotein 2/0.451
3e6oA55Nitric oxide synthase, inducible1.14.13.390.451
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.451
3t7vSAM3-methylornithine synthase/0.451
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.451
3jszUPGUncharacterized protein/0.450
2e20B4PPropionate kinase/0.449
2fycGDUBeta-1,4-galactosyltransferase 12.4.10.449
5c1gGDUHisto-blood group ABO system transferase/0.449
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.448
3imgBZ2Pantothenate synthetase6.3.2.10.448
3oadLPORenin3.4.23.150.448
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.448
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
3tm5SFGUncharacterized protein/0.447
3ts1TYATyrosine--tRNA ligase6.1.1.10.447
4y4jLNREndothiapepsin3.4.23.220.447
5fd8A5APutative carboxypeptidase yocD/0.447
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.446
4s1b2BALmo1466 protein/0.446
5fl3ADPPili retraction protein PilT/0.446
1hbvGANGag-Pol polyprotein/0.445
1ia1NDPDihydrofolate reductase1.5.1.30.445
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.445
2vkdUPGCytotoxin L/0.445
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.445
1zp4FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.444
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.444
3e7gAT2Nitric oxide synthase, inducible1.14.13.390.444
3e7iB2Nitric oxide synthase, inducible1.14.13.390.444
3zkyWT4Isopenicillin N synthase1.21.3.10.444
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.444
1n2eAPCPantothenate synthetase6.3.2.10.443
1tv8SAMGTP 3',8-cyclase4.1.99.180.443
5dhhDGWNociceptin receptor/0.443
2vs5GDUN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.442
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.442
3t7qRB4Endothiapepsin3.4.23.220.442
3ufqHW5Nitric oxide synthase, brain1.14.13.390.442
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.442
1rwbNADGlucose 1-dehydrogenase1.1.1.470.441
2v00V15Endothiapepsin3.4.23.220.441
3mj4URMUDP-galactopyranose mutase/0.441
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.441
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.440
1qvuPRLHTH-type transcriptional regulator QacR/0.440
1ty9FMNPhenazine biosynthesis protein PhzG1.40.440
1zzrDP9Nitric oxide synthase, brain1.14.13.390.440
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.440
3jx5J14Nitric oxide synthase, brain1.14.13.390.440
4avgSL6Polymerase acidic protein/0.440
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.440