scPDB - Distribution of Binding site Similarity values of 1h66 entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1h66	RH1	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1h66	RH1	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	1.000
1kbo	340	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.622
3jsx	CC2	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.615
1gg5	E09	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.592
1h69	ARH	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.573
4cf6	CBD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.572
4bft	ZVT	Pantothenate kinase	2.7.1.33	0.481
2ha6	SCK	Acetylcholinesterase	3.1.1.7	0.476
1mcz	RMN	Benzoylformate decarboxylase	4.1.1.7	0.472
2j83	BAT	Ulilysin	3.4.24	0.472
1xl8	152	Peroxisomal carnitine O-octanoyltransferase	2.3.1.137	0.470
2rh1	CAU	Beta-2 adrenergic receptor	/	0.470
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.469
3u5y	SCG	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.468
4ey6	GNT	Acetylcholinesterase	3.1.1.7	0.468
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.468
2xui	TZ5	Acetylcholinesterase	3.1.1.7	0.467
3qe2	FMN	NADPH--cytochrome P450 reductase	/	0.466
3wag	TYD	Glycosyltransferase	/	0.465
1fml	RTL	Retinol dehydratase	/	0.462
4y0k	NAP	AntE	/	0.462
4b7z	Q4Q	Acetylcholinesterase	3.1.1.7	0.461
5d6l	CAU	Beta-2 adrenergic receptor	/	0.461
3frk	TQP	QdtB	/	0.460
4qzu	RTL	Retinol-binding protein 2	/	0.460
2a94	AP0	L-lactate dehydrogenase	1.1.1.27	0.459
1amo	FMN	NADPH--cytochrome P450 reductase	/	0.458
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.458
5dp2	NAP	CurF	/	0.458
1q83	TZ5	Acetylcholinesterase	3.1.1.7	0.457
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.457
4f1l	0RY	Poly [ADP-ribose] polymerase 14	2.4.2.30	0.457
2g1s	4IG	Renin	3.4.23.15	0.456
2iod	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.456
3c1t	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.456
4m0f	1YK	Acetylcholinesterase	3.1.1.7	0.456
2bn4	FMN	NADPH--cytochrome P450 reductase	/	0.455
2xuf	TZ4	Acetylcholinesterase	3.1.1.7	0.455
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.454
3hl0	NAD	Maleylacetate reductase	/	0.453
1k4m	NAD	Nicotinate-nucleotide adenylyltransferase	2.7.7.18	0.452
1u65	CP0	Acetylcholinesterase	3.1.1.7	0.452
2a5h	SAM	L-lysine 2,3-aminomutase	5.4.3.2	0.452
2xuh	TZ4	Acetylcholinesterase	3.1.1.7	0.452
4rn6	15U	Prothrombin	3.4.21.5	0.452
4x7u	ZM3	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.452
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.451
3ggs	2FD	Purine nucleoside phosphorylase	2.4.2.1	0.451
5irn	ADP	Nucleotide binding oligomerization domain containing 2	/	0.451
2ycx	P32	Beta-1 adrenergic receptor	/	0.451
2j3q	TFL	Acetylcholinesterase	3.1.1.7	0.450
3bv7	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.450
1i5r	HYC	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.449
2zsd	COA	Pantothenate kinase	2.7.1.33	0.449
3dys	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.448
4bca	FAD	Alkyldihydroxyacetonephosphate synthase, peroxisomal	2.5.1.26	0.448
2gv8	NDP	Thiol-specific monooxygenase	1.14.13	0.447
3f63	GTX	Glutathione transferase GST1-4	/	0.447
1bil	0IU	Renin	3.4.23.15	0.446
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.446
2a58	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.446
2xi4	AFT	Acetylcholinesterase	3.1.1.7	0.446
3dyl	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.446
1kqw	RTL	Cellular retinol-binding protein type II	/	0.445
3ziu	LSS	Leucyl-tRNA synthetase	/	0.445
5jqh	CAU	Beta-2 adrenergic receptor	/	0.445
1q84	TZ4	Acetylcholinesterase	3.1.1.7	0.444
2g24	7IG	Renin	3.4.23.15	0.444
2xuo	TZ4	Acetylcholinesterase	3.1.1.7	0.444
3g1r	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.444
4g3j	VNT	Lanosterol 14-alpha-demethylase	/	0.444
1w87	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.443
2a9y	26A	Adenosine kinase	2.7.1.20	0.443
2cmf	F11	Acetylcholinesterase	3.1.1.7	0.443
2uuv	FAD	Alkyldihydroxyacetonephosphate synthase	2.5.1.26	0.443
4fhd	0TT	Spore photoproduct lyase	/	0.443
4nwi	CTN	7-methylguanosine phosphate-specific 5'-nucleotidase	/	0.443
1h22	E10	Acetylcholinesterase	3.1.1.7	0.442
1qti	GNT	Acetylcholinesterase	3.1.1.7	0.442
1w76	GNT	Acetylcholinesterase	3.1.1.7	0.442
2rqf	JH3	Hemolymph juvenile hormone binding protein	/	0.442
2xuj	TZ5	Acetylcholinesterase	3.1.1.7	0.442
3af0	GDP	Pantothenate kinase	2.7.1.33	0.442
5c1g	GDU	Histo-blood group ABO system transferase	/	0.442
2hdj	NDP	Aldo-keto reductase family 1 member C2	/	0.441
3r8h	ZOM	Aldo-keto reductase family 1 member C3	/	0.441
3zku	HCV	Isopenicillin N synthase	1.21.3.1	0.441
1c7o	PPG	Hemolysin	/	0.440
2cek	N8T	Acetylcholinesterase	3.1.1.7	0.440
2f38	15M	Aldo-keto reductase family 1 member C3	/	0.440
3af1	GDP	Pantothenate kinase	2.7.1.33	0.440
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.440
3gam	MXX	Ribosyldihydronicotinamide dehydrogenase [quinone]	/	0.440
4bfu	ZVU	Pantothenate kinase	2.7.1.33	0.440