sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4i0a | CMP | cAMP-activated global transcriptional regulator CRP |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4i0a | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.991 | |
| 4i09 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.944 | |
| 4hzf | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.942 | |
| 3rou | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.936 | |
| 3kcc | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.912 | |
| 4ft8 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.904 | |
| 3ryp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.902 | |
| 1i5z | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.901 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.899 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.898 | |
| 4i0b | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.891 | |
| 3qop | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.886 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.869 | |
| 3n4m | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.867 | |
| 3rpq | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.865 | |
| 3ryr | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.863 | |
| 3rdi | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.854 | |
| 4r8h | SP1 | cAMP-activated global transcriptional regulator CRP | / | 0.848 | |
| 1zrd | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.813 | |
| 2gzw | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.810 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.788 | |
| 3u10 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.787 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.784 | |
| 1cx4 | CMP | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.766 | |
| 4hbn | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.764 | |
| 1q3e | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.753 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.749 | |
| 4i01 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.744 | |
| 1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.743 | |
| 1cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.742 | |
| 1q5o | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.741 | |
| 3bpz | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.741 | |
| 4mgk | CMP | Rap guanine nucleotide exchange factor 4 | / | 0.738 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.737 | |
| 1hw5 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.736 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.736 | |
| 3u0z | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | / | 0.736 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.728 | |
| 3of1 | CMP | cAMP-dependent protein kinase regulatory subunit | / | 0.726 | |
| 4ku7 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.726 | |
| 2ptm | CMP | Hyperpolarization-activated (Ih) channel | / | 0.724 | |
| 3u11 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.721 | |
| 4d7s | PCG | Uncharacterized protein | / | 0.719 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.718 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.716 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.716 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.715 | |
| 4d7t | CMP | Uncharacterized protein | / | 0.714 | |
| 3cl1 | PCG | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.713 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.713 | |
| 3shr | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.710 | |
| 4z07 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.705 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.704 | |
| 1g6n | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.702 | |
| 4kg1 | PCG | Diguanylate cyclase | / | 0.699 | |
| 1zrc | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.696 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.694 | |
| 3plq | RP2 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.693 | |
| 3od0 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.685 | |
| 2k0g | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.683 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.679 | |
| 3oii | SAH | Ribosomal RNA small subunit methyltransferase NEP1 | / | 0.666 | |
| 4jwf | SAH | tRNA (guanine(9)-N1)-methyltransferase | / | 0.666 | |
| 1ruo | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.664 | |
| 4ev0 | CMP | Cyclic AMP receptor protein | / | 0.664 | |
| 3ogj | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.663 | |
| 5a7y | SAH | tRNA (adenine(9)-N1)-methyltransferase | 2.1.1.218 | 0.661 | |
| 2ioa | ADP | Bifunctional glutathionylspermidine synthetase/amidase | / | 0.656 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.653 | |
| 2io7 | ANP | Bifunctional glutathionylspermidine synthetase/amidase | / | 0.652 | |
| 3ab8 | ATP | Uncharacterized protein | / | 0.652 | |
| 4jwj | SAH | tRNA (guanine(9)-N1)-methyltransferase | / | 0.651 |