Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4c3s NAD Aldehyde Dehydrogenase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4c3s NADAldehyde Dehydrogenase / 1.126
2bhp NAD1-pyrroline-5-carboxylate dehydrogenase / 0.766
2ehq NAP1-pyrroline-5-carboxylate dehydrogenase / 0.761
1t90 NADMalonate-semialdehyde dehydrogenase 1.2.1.27 0.755
4pxn NADAldehyde dehydrogenase family 7 member B4 / 0.744
2j6l NAIAlpha-aminoadipic semialdehyde dehydrogenase 1.2.1.31 0.742
2id2 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.741
2j40 NAD1-pyrroline-5-carboxylate dehydrogenase / 0.741
1a4z NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.733
2jg7 NADAntiquitin / 0.726
1uxr NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.723
3rhq NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.723
3rhl NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.721
3haz NADBifunctional protein PutA / 0.720
3b4w NADAldehyde dehydrogenase family protein / 0.719
2eii NAD1-pyrroline-5-carboxylate dehydrogenase / 0.715
1o04 NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.712
2ehu NAD1-pyrroline-5-carboxylate dehydrogenase / 0.709
4i8p NADAminoaldehyde dehydrogenase 1 / 0.707
2eit NAD1-pyrroline-5-carboxylate dehydrogenase / 0.702
4oe2 NAD2-aminomuconate 6-semialdehyde dehydrogenase / 0.699
4v37 NADBetaine aldehyde dehydrogenase, chloroplastic 1.2.1.8 0.692
4a0m NADBetaine aldehyde dehydrogenase, chloroplastic 1.2.1.8 0.687
4pz2 NADAldehyde dehydrogenase 2-6 / 0.687
2d4e NAD5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831] / 0.685
3lns NAPNAD(P)-dependent benzaldehyde dehydrogenase 1.2.1.28 0.685
1uxt NADNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.683
4i8q NADPutative betaine aldehyde dehyrogenase / 0.683
4ihi NADProbable pyrroline-5-carboxylate dehydrogenase RocA / 0.683
2j5n NAD1-pyrroline-5-carboxylate dehydrogenase / 0.678
1uxp NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.677
2y5d NAP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase / 0.675
3rhr NDPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.675
4gnz NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.675
4jdc NADProbable pyrroline-5-carboxylate dehydrogenase RocA / 0.675
4gkv NADAlcohol dehydrogenase, propanol-preferring 1.1.1.1 0.674
2bja NAD1-pyrroline-5-carboxylate dehydrogenase / 0.673
3efv NADPutative succinate-semialdehyde dehydrogenase / 0.669
5a02 NAPGlucose-fructose oxidoreductase / 0.668
5a05 NDPGlucose-fructose oxidoreductase / 0.665
1o9j NADAldehyde dehydrogenase, cytosolic 1 1.2.1.3 0.662
1zh8 NAPUncharacterized protein / 0.661
2euh NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.658
2imp NAILactaldehyde dehydrogenase 1.2.1.22 0.658
2g8y NADHydroxycarboxylate dehydrogenase B / 0.655
4pxl NADAldehyde dehydrogenase3 / 0.655
4nmj NAPAldehyde dehydrogenase / 0.654
1uxn NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.653
2qe0 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.653
4i3w NADAldehyde dehydrogenase (NAD+) / 0.653
4i9b NADPutative betaine aldehyde dehyrogenase / 0.653
3rhd NAPLactaldehyde dehydrogenase 1.2.1.22 0.652
1h6b NDPGlucose--fructose oxidoreductase 1.1.99.28 0.650
2glx NDP1,5-anhydro-D-fructose reductase / 0.650
4go2 TAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.650