Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rhd NAP Lactaldehyde dehydrogenase 1.2.1.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3rhd NAPLactaldehyde dehydrogenase 1.2.1.22 0.922
4nmk NAPAldehyde dehydrogenase / 0.804
3rhh NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.750
4h73 NDPAldehyde dehydrogenase / 0.747
3iwj NADAminoaldehyde dehydrogenase / 0.742
2qe0 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.736
4itb NDPSuccinate-semialdehyde dehydrogenase / 0.732
4nmj NAPAldehyde dehydrogenase / 0.724
4fr8 ADPAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.720
4x2q NADRetinal dehydrogenase 2 1.2.1.36 0.718
4i3v NADAldehyde dehydrogenase (NAD+) / 0.714
2id2 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.709
1o9j NADAldehyde dehydrogenase, cytosolic 1 1.2.1.3 0.708
2o2r NDPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.708
3n83 ADPAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.703
3b4w NADAldehyde dehydrogenase family protein / 0.701
2o2q NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.698
1qi1 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.693
4pz2 NADAldehyde dehydrogenase 2-6 / 0.691
1uxr NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.690
4zvy NADAlpha-aminoadipic semialdehyde dehydrogenase 1.2.1.31 0.688
1nzz NAIAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.687
4go2 TAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.687
2eit NAD1-pyrroline-5-carboxylate dehydrogenase / 0.686
2esd NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.686
2d4e NAD5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831] / 0.685
2j40 NAD1-pyrroline-5-carboxylate dehydrogenase / 0.685
1o01 NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.683
1o02 NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.683
2bhp NAD1-pyrroline-5-carboxylate dehydrogenase / 0.683
1nzx NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.678
1uxu NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.677
2y5d NAP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase / 0.677
1nzw NAIAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.676
3zqa NDPNAD/NADP-dependent betaine aldehyde dehydrogenase / 0.673
2bja NAD1-pyrroline-5-carboxylate dehydrogenase / 0.672
2onm NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.668
2wme NAPNAD/NADP-dependent betaine aldehyde dehydrogenase / 0.661
2xdr NDPNAD/NADP-dependent betaine aldehyde dehydrogenase / 0.658
1uxt NADNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.657
4c3s NADAldehyde Dehydrogenase / 0.652
2onp NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.651