scPDB - Distribution of Cavity Similarity values of 4fr1 entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	0.748
1y5v	NE8	Queuine tRNA-ribosyltransferase	2.4.2.29	0.590
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.589
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.587
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.576
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.573
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.572
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.567
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.564
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.557
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.545
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29	0.541
2pot	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.540
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	0.538
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.535
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.535
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.531
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.529
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.523
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.520
1p0e	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.519
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.519
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	0.514
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.501
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.500
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.499
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.486
4hqv	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.483
1q65	BHB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.479
4fvz	4KJ	Nitric oxide synthase, brain	1.14.13.39	0.466
1pxg	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.465
3akz	GSU	Glutamate--tRNA ligase 2	/	0.461
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.460
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.459
4ug7	H4B	Nitric oxide synthase oxygenase	1.14.13.165	0.458
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.456
2c94	TSF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.456
3t4e	NAD	Quinate/shikimate dehydrogenase	/	0.454
4b11	7I1	Glycylpeptide N-tetradecanoyltransferase	/	0.453
4b14	4XB	Glycylpeptide N-tetradecanoyltransferase	/	0.453
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.453
4gcx	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.452
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.451
2g28	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.450
4h1e	10J	Beta-secretase 1	3.4.23.46	0.449
2in6	839	Wee1-like protein kinase	2.7.10.2	0.446
3g4i	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.446
4bb6	HD1	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.446
3abx	RCB	Glucanase	/	0.445
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.444
1x8b	824	Wee1-like protein kinase	2.7.10.2	0.444
2f7x	4EA	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.444
2fm5	M99	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.444
4wx2	F6F	Tryptophan synthase alpha chain	/	0.444
4wx2	F6F	Tryptophan synthase beta chain	4.2.1.20	0.444
2gjl	FMN	Nitronate monooxygenase	1.13.12.16	0.443
3nmh	PYV	Abscisic acid receptor PYL2	/	0.443
4b12	C23	Glycylpeptide N-tetradecanoyltransferase	/	0.443
4bbh	YBN	Glycylpeptide N-tetradecanoyltransferase	/	0.443
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.443
2ivp	ATP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.442
3e7i	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.442
4p9d	TMP	Deoxycytidylate deaminase	/	0.442
1sgu	MK1	Gag-Pol polyprotein	3.4.23.16	0.441
1uho	VDN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.441
1w19	T4P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.441
3vwe	COA	Alpha-tubulin N-acetyltransferase 1	/	0.441
2a4x	BLM	Mitomycin-binding protein	/	0.440
3h4v	NAP	Pteridine reductase 1	1.5.1.33	0.440
4ug5	H4B	Nitric oxide synthase oxygenase	1.14.13.165	0.440