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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3py0SU9Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3py0SU9Cyclin-dependent kinase 22.7.11.221.000
3unk0BYCyclin-dependent kinase 22.7.11.220.610
3r9dX6BCyclin-dependent kinase 22.7.11.220.568
4fko20KCyclin-dependent kinase 22.7.11.220.561
3qtxX43Cyclin-dependent kinase 22.7.11.220.556
3rpv26ZCyclin-dependent kinase 22.7.11.220.554
2xmyCDKCyclin-dependent kinase 22.7.11.220.548
3rmf20ZCyclin-dependent kinase 22.7.11.220.547
3unj0BXCyclin-dependent kinase 22.7.11.220.538
3s1h56ZCyclin-dependent kinase 22.7.11.220.530
3sw418KCyclin-dependent kinase 22.7.11.220.529
3rak03ZCyclin-dependent kinase 22.7.11.220.526
4acm7YGCyclin-dependent kinase 22.7.11.220.525
3rni21ZCyclin-dependent kinase 22.7.11.220.520
1pxmCK5Cyclin-dependent kinase 22.7.11.220.517
3qtuX44Cyclin-dependent kinase 22.7.11.220.517
3sw719KCyclin-dependent kinase 22.7.11.220.516
3qzgX67Cyclin-dependent kinase 22.7.11.220.512
3rpy27ZCyclin-dependent kinase 22.7.11.220.512
3qu0X40Cyclin-dependent kinase 22.7.11.220.509
3ral04ZCyclin-dependent kinase 22.7.11.220.509
3rk909ZCyclin-dependent kinase 22.7.11.220.509
3rk507ZCyclin-dependent kinase 22.7.11.220.508
1di8DTQCyclin-dependent kinase 22.7.11.220.507
4ek816KCyclin-dependent kinase 22.7.11.220.507
3rk708ZCyclin-dependent kinase 22.7.11.220.506
3qtzX42Cyclin-dependent kinase 22.7.11.220.505
4fkq42KCyclin-dependent kinase 22.7.11.220.505
4fkr45KCyclin-dependent kinase 22.7.11.220.503
1ke5LS1Cyclin-dependent kinase 22.7.11.220.502
4fks46KCyclin-dependent kinase 22.7.11.220.502
3qqhX0ACyclin-dependent kinase 22.7.11.220.501
4fkt48KCyclin-dependent kinase 22.7.11.220.499
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.494
3rjc06ZCyclin-dependent kinase 22.7.11.220.492
3ti1B49Cyclin-dependent kinase 22.7.11.220.490
4bgh3I6Cyclin-dependent kinase 22.7.11.220.490
4fkv61KCyclin-dependent kinase 22.7.11.220.490
1y91CT9Cyclin-dependent kinase 22.7.11.220.489
1urwI1PCyclin-dependent kinase 22.7.11.220.486
4ez30S0Cyclin-dependent kinase 22.7.11.220.485
4fkw62KCyclin-dependent kinase 22.7.11.220.485
3qtrX36Cyclin-dependent kinase 22.7.11.220.484
4fkpLS5Cyclin-dependent kinase 22.7.11.220.482
2w06FRVCyclin-dependent kinase 22.7.11.220.479
3r1sX73Cyclin-dependent kinase 22.7.11.220.479
3r9hZ67Cyclin-dependent kinase 22.7.11.220.479
1ke6LS2Cyclin-dependent kinase 22.7.11.220.478
1p2a5BNCyclin-dependent kinase 22.7.11.220.478
2iw84SPCyclin-dependent kinase 22.7.11.220.477
3pxyJWSCyclin-dependent kinase 22.7.11.220.474
2btsU32Cyclin-dependent kinase 22.7.11.220.473
2w1hL0FCyclin-dependent kinase 22.7.11.220.471
3qwjX6ACyclin-dependent kinase 22.7.11.220.471
3qzhX69Cyclin-dependent kinase 22.7.11.220.471
3lfnA27Cyclin-dependent kinase 22.7.11.220.470
1ke9LS5Cyclin-dependent kinase 22.7.11.220.469
2b52D42Cyclin-dependent kinase 22.7.11.220.469
1ke7LS3Cyclin-dependent kinase 22.7.11.220.468
3rpo24ZCyclin-dependent kinase 22.7.11.220.468
1ykr628Cyclin-dependent kinase 22.7.11.220.467
1gih1PUCyclin-dependent kinase 22.7.11.220.466
2btrU73Cyclin-dependent kinase 22.7.11.220.466
2c6iDT1Cyclin-dependent kinase 22.7.11.220.466
1ke8LS4Cyclin-dependent kinase 22.7.11.220.464
1oitHDTCyclin-dependent kinase 22.7.11.220.463
3r9oZ71Cyclin-dependent kinase 22.7.11.220.461
1ckpPVBCyclin-dependent kinase 22.7.11.220.459
4ek610KCyclin-dependent kinase 22.7.11.220.459
2vttLZDCyclin-dependent kinase 22.7.11.220.458
3ezvEZVCyclin-dependent kinase 22.7.11.220.458
3qqkX02Cyclin-dependent kinase 22.7.11.220.458
3r8lZ30Cyclin-dependent kinase 22.7.11.220.458
3rm618ZCyclin-dependent kinase 22.7.11.220.457
2c6o4SPCyclin-dependent kinase 22.7.11.220.456
2a0cCK9Cyclin-dependent kinase 22.7.11.220.455
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.455
1pxkCK3Cyclin-dependent kinase 22.7.11.220.453
2uzoC62Cyclin-dependent kinase 22.7.11.220.453
3r71X86Cyclin-dependent kinase 22.7.11.220.452
1vyzN5BCyclin-dependent kinase 22.7.11.220.450
3sqq99ZCyclin-dependent kinase 22.7.11.220.450
1gij2PUCyclin-dependent kinase 22.7.11.220.449
3r8zZ63Cyclin-dependent kinase 22.7.11.220.449
1gii1PUCyclin-dependent kinase 22.7.11.220.445
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.445
3rzb02ZCyclin-dependent kinase 22.7.11.220.445
1pxlCK4Cyclin-dependent kinase 22.7.11.220.444
3fz1B98Cyclin-dependent kinase 22.7.11.220.444
3qxoX65Cyclin-dependent kinase 22.7.11.220.444
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.443
3ixj586Beta-secretase 13.4.23.460.443
3ql8X01Cyclin-dependent kinase 22.7.11.220.443
3qtqX35Cyclin-dependent kinase 22.7.11.220.443
2r3lSCWCyclin-dependent kinase 22.7.11.220.442
3r7yZ04Cyclin-dependent kinase 22.7.11.220.442
3r8vZ62Cyclin-dependent kinase 22.7.11.220.442
3uli1N3Cyclin-dependent kinase 22.7.11.220.442
1h1s4SPCyclin-dependent kinase 22.7.11.220.441
1oiyN41Cyclin-dependent kinase 22.7.11.220.440
2bheBRYCyclin-dependent kinase 22.7.11.220.440
3cid318Beta-secretase 13.4.23.460.440
3iggEFQCyclin-dependent kinase 22.7.11.220.440
3r6xX84Cyclin-dependent kinase 22.7.11.220.440