sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3n5b | ADP | Nitrogen regulatory protein P-II |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3n5b | ADP | Nitrogen regulatory protein P-II | / | 1.000 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.470 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.461 | |
| 1um8 | ADP | ATP-dependent Clp protease ATP-binding subunit ClpX | / | 0.459 | |
| 4dja | FAD | (6-4) photolyase | / | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.455 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.448 | |
| 4co0 | ADP | Nitrogen regulatory protein P-II 1 | / | 0.447 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.446 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 4oaq | NDP | R-specific carbonyl reductase | / | 0.443 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.442 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.440 |