sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3iu9 | T07 | Methionine aminopeptidase 2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 1.000 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.576 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.559 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.545 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.529 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.526 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.502 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.499 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.491 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.483 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.480 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.480 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.476 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.474 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.469 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.468 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.466 | |
| 2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.466 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.466 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.465 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.465 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.463 | |
| 4ikr | PVP | Methionine aminopeptidase 1 | / | 0.459 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 0.454 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.451 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.451 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.449 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.449 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.447 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.444 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.441 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.441 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.441 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 |