sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2vr1	ATF	Biotin carboxylase	6.3.4.14

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2vr1	ATF	Biotin carboxylase	6.3.4.14	1.000
2w6q	OA5	Biotin carboxylase	6.3.4.14	0.528
2w6z	L21	Biotin carboxylase	6.3.4.14	0.507
2v5a	LZL	Biotin carboxylase	6.3.4.14	0.498
4mv8	ACP	Biotin carboxylase	6.3.4.14	0.485
2w6o	OA3	Biotin carboxylase	6.3.4.14	0.484
2j9g	ANP	Biotin carboxylase	6.3.4.14	0.483
4mv1	ADP	Biotin carboxylase	6.3.4.14	0.483
3jzi	JZL	Biotin carboxylase	6.3.4.14	0.475
4mv4	ACP	Biotin carboxylase	6.3.4.14	0.467
2w6m	OA1	Biotin carboxylase	6.3.4.14	0.461
2v58	LZJ	Biotin carboxylase	6.3.4.14	0.460
3g8d	ADP	Biotin carboxylase	6.3.4.14	0.449
2w71	L23	Biotin carboxylase	6.3.4.14	0.443