sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2giu | FBR | Estrogen receptor beta |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2giu | FBR | Estrogen receptor beta | / | 1.000 | |
| 2z4b | DC8 | Estrogen receptor beta | / | 0.564 | |
| 1nde | MON | Estrogen receptor beta | / | 0.525 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.509 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.501 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.500 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.498 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.497 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.495 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.494 | |
| 2pog | WST | Estrogen receptor | / | 0.490 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.489 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.488 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1osv | CHC | Bile acid receptor | / | 0.487 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.486 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.483 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.477 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.477 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.474 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1err | RAL | Estrogen receptor | / | 0.473 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1l2i | ETC | Estrogen receptor | / | 0.473 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4pxm | EST | Estrogen receptor | / | 0.473 | |
| 1uom | PTI | Estrogen receptor | / | 0.472 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.472 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 4crs | AGS | Serine/threonine-protein kinase N2 | 2.7.11.13 | 0.472 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.471 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.470 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.470 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.469 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.469 | |
| 1x7e | 244 | Estrogen receptor | / | 0.468 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.467 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.465 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 3ews | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.464 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4fz6 | 0VG | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.464 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.464 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.463 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.463 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 4j26 | EST | Estrogen receptor beta | / | 0.463 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.463 | |
| 1yin | CM3 | Estrogen receptor | / | 0.462 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.462 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.462 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.462 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.462 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.461 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.460 | |
| 3cxh | SMA | Cytochrome b | / | 0.460 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.460 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.460 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.460 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.460 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.459 | |
| 3h18 | PMS | Esterase/lipase | / | 0.459 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.459 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1kqg | HQO | Formate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit | / | 0.458 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.458 | |
| 3eej | 53R | Uncharacterized protein | / | 0.458 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4iu7 | 1GM | Estrogen receptor | / | 0.458 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.458 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.458 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 2dub | CO8 | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.457 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.457 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.457 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.457 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.457 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.457 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.457 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.456 | |
| 2px2 | SAH | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.455 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.455 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.455 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.455 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.454 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 4fyn | 0VE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.454 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.454 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.453 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 3r7y | Z04 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.453 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.453 | |
| 4ivw | 1GJ | Estrogen receptor | / | 0.453 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.453 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.452 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.452 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.452 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.452 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1zuc | T98 | Progesterone receptor | / | 0.451 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.451 | |
| 3up3 | XCA | aceDAF-12 | / | 0.451 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.451 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.451 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.451 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.451 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 1qv1 | CZH | Obelin | / | 0.450 | |
| 1ztf | XYA | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.450 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 2jj3 | JJ3 | Estrogen receptor beta | / | 0.450 | |
| 3elu | SAM | Methyltransferase | / | 0.450 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.450 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.450 | |
| 5hyr | EST | Estrogen receptor | / | 0.450 | |
| 2aru | ATP | Lipoate-protein ligase A subunit 1 | / | 0.449 | |
| 2p15 | EZT | Estrogen receptor | / | 0.449 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.449 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.449 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.449 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.448 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.448 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.448 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.448 | |
| 4pd6 | URI | Nucleoside permease | / | 0.448 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.447 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.447 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.447 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4bqu | CLR | Japanin | / | 0.447 | |
| 5dxg | EST | Estrogen receptor | / | 0.447 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 2qgt | EED | Estrogen receptor | / | 0.446 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 3ffi | 3OB | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.446 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.446 | |
| 1kyo | SMA | Cytochrome b | / | 0.445 | |
| 1rt2 | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1tz8 | DES | Transthyretin | / | 0.445 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.445 | |
| 2j7y | E3O | Estrogen receptor beta | / | 0.445 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.445 | |
| 3aba | FLI | Cytochrome P450 | / | 0.445 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.445 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.445 | |
| 4fm5 | DF0 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4n1f | CZH | Obelin | / | 0.445 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.445 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.444 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.444 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.444 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.444 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.444 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3nwy | GTP | Uridylate kinase | / | 0.444 | |
| 3oll | EST | Estrogen receptor beta | / | 0.444 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.444 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.444 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4ktc | 1X3 | Genome polyprotein | 3.4.21.98 | 0.444 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.443 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.443 | |
| 3rr3 | FLR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 3uud | EST | Estrogen receptor | / | 0.443 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.443 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.443 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.443 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.442 | |
| 1u3r | 338 | Estrogen receptor beta | / | 0.442 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.442 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 2y01 | Y01 | Beta-1 adrenergic receptor | / | 0.442 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.442 | |
| 3hv6 | R39 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.442 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.442 | |
| 4c2x | NHW | Glycylpeptide N-tetradecanoyltransferase 2 | / | 0.442 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.442 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.441 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.441 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.441 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.441 | |
| 1ie4 | T44 | Transthyretin | / | 0.440 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.440 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3eld | SFG | Methyltransferase | / | 0.440 | |
| 3h1j | SMA | Cytochrome b | / | 0.440 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.440 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4e4n | 0NL | Tyrosine-protein kinase JAK1 | / | 0.440 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4gmg | NAP | Yersiniabactin biosynthetic protein YbtU | / | 0.440 | |
| 4jap | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 |