sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ga2 | A19 | Methionine aminopeptidase 2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 1.000 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.705 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.697 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.696 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.656 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.654 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.646 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.604 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.587 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.577 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.537 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.476 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.472 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.456 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.455 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.444 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.442 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.442 |