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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2b52D42Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2b52D42Cyclin-dependent kinase 22.7.11.221.000
3rjc06ZCyclin-dependent kinase 22.7.11.220.590
3rpv26ZCyclin-dependent kinase 22.7.11.220.581
3lfnA27Cyclin-dependent kinase 22.7.11.220.569
3qu0X40Cyclin-dependent kinase 22.7.11.220.551
3ezvEZVCyclin-dependent kinase 22.7.11.220.547
3r1yX76Cyclin-dependent kinase 22.7.11.220.547
3rak03ZCyclin-dependent kinase 22.7.11.220.541
3rm618ZCyclin-dependent kinase 22.7.11.220.537
3s1h56ZCyclin-dependent kinase 22.7.11.220.527
1g5sI17Cyclin-dependent kinase 22.7.11.220.523
3rk909ZCyclin-dependent kinase 22.7.11.220.523
2btrU73Cyclin-dependent kinase 22.7.11.220.517
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.514
3r7yZ04Cyclin-dependent kinase 22.7.11.220.514
3r8vZ62Cyclin-dependent kinase 22.7.11.220.511
3rpo24ZCyclin-dependent kinase 22.7.11.220.509
4fkv61KCyclin-dependent kinase 22.7.11.220.508
3r8lZ30Cyclin-dependent kinase 22.7.11.220.507
2c6o4SPCyclin-dependent kinase 22.7.11.220.506
3qtrX36Cyclin-dependent kinase 22.7.11.220.503
3sqq99ZCyclin-dependent kinase 22.7.11.220.503
1y91CT9Cyclin-dependent kinase 22.7.11.220.501
2uznC96Cyclin-dependent kinase 22.7.11.220.499
3qwjX6ACyclin-dependent kinase 22.7.11.220.498
3rni21ZCyclin-dependent kinase 22.7.11.220.498
4acm7YGCyclin-dependent kinase 22.7.11.220.498
4fki09KCyclin-dependent kinase 22.7.11.220.498
2xmyCDKCyclin-dependent kinase 22.7.11.220.497
1oitHDTCyclin-dependent kinase 22.7.11.220.496
1ke5LS1Cyclin-dependent kinase 22.7.11.220.494
1ykr628Cyclin-dependent kinase 22.7.11.220.494
3sw418KCyclin-dependent kinase 22.7.11.220.494
4ek816KCyclin-dependent kinase 22.7.11.220.492
1pxoCK7Cyclin-dependent kinase 22.7.11.220.491
3rk708ZCyclin-dependent kinase 22.7.11.220.491
2vv9IM9Cyclin-dependent kinase 22.7.11.220.489
3qtxX43Cyclin-dependent kinase 22.7.11.220.489
3r71X86Cyclin-dependent kinase 22.7.11.220.488
3lfqA28Cyclin-dependent kinase 22.7.11.220.487
3qzgX67Cyclin-dependent kinase 22.7.11.220.485
2w1hL0FCyclin-dependent kinase 22.7.11.220.484
3rkb12ZCyclin-dependent kinase 22.7.11.220.484
2a0cCK9Cyclin-dependent kinase 22.7.11.220.480
4ek610KCyclin-dependent kinase 22.7.11.220.479
4fkt48KCyclin-dependent kinase 22.7.11.220.479
3qxpX64Cyclin-dependent kinase 22.7.11.220.478
1pxmCK5Cyclin-dependent kinase 22.7.11.220.477
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.476
3qtzX42Cyclin-dependent kinase 22.7.11.220.476
2r3lSCWCyclin-dependent kinase 22.7.11.220.475
3r1sX73Cyclin-dependent kinase 22.7.11.220.475
1aq1STUCyclin-dependent kinase 22.7.11.220.474
2a4lRRCCyclin-dependent kinase 22.7.11.220.474
3pj8404Cyclin-dependent kinase 22.7.11.220.472
2vtsLZCCyclin-dependent kinase 22.7.11.220.471
1h1r6CPCyclin-dependent kinase 22.7.11.220.470
1ke7LS3Cyclin-dependent kinase 22.7.11.220.470
1w0xOLOCyclin-dependent kinase 22.7.11.220.470
2uzoC62Cyclin-dependent kinase 22.7.11.220.470
4fkq42KCyclin-dependent kinase 22.7.11.220.470
2r3jSCJCyclin-dependent kinase 22.7.11.220.469
3r83Z14Cyclin-dependent kinase 22.7.11.220.468
4ez30S0Cyclin-dependent kinase 22.7.11.220.468
4fkpLS5Cyclin-dependent kinase 22.7.11.220.468
2btsU32Cyclin-dependent kinase 22.7.11.220.466
2r64740Cyclin-dependent kinase 22.7.11.220.466
1h1s4SPCyclin-dependent kinase 22.7.11.220.465
1ckpPVBCyclin-dependent kinase 22.7.11.220.464
2r3kSCQCyclin-dependent kinase 22.7.11.220.464
3r7uX96Cyclin-dependent kinase 22.7.11.220.464
1di8DTQCyclin-dependent kinase 22.7.11.220.461
3qtuX44Cyclin-dependent kinase 22.7.11.220.461
1ke9LS5Cyclin-dependent kinase 22.7.11.220.459
1w8cN69Cyclin-dependent kinase 22.7.11.220.459
4fks46KCyclin-dependent kinase 22.7.11.220.459
4fkw62KCyclin-dependent kinase 22.7.11.220.458
1e1xNW1Cyclin-dependent kinase 22.7.11.220.456
1v1k3FPCyclin-dependent kinase 22.7.11.220.456
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.455
2vtrLZBCyclin-dependent kinase 22.7.11.220.453
3ddqRRCCyclin-dependent kinase 22.7.11.220.453
3iggEFQCyclin-dependent kinase 22.7.11.220.453
3r9oZ71Cyclin-dependent kinase 22.7.11.220.453
1oirHDYCyclin-dependent kinase 22.7.11.220.452
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.452
1oguST8Cyclin-dependent kinase 22.7.11.220.451
3s2pPMUCyclin-dependent kinase 22.7.11.220.450
4kd11QKCyclin-dependent kinase 22.7.11.220.450
1urwI1PCyclin-dependent kinase 22.7.11.220.449
3qruX19Cyclin-dependent kinase 22.7.11.220.449
1ke6LS2Cyclin-dependent kinase 22.7.11.220.448
3r7vZ02Cyclin-dependent kinase 22.7.11.220.448
4fkj11KCyclin-dependent kinase 22.7.11.220.448
3r9hZ67Cyclin-dependent kinase 22.7.11.220.447
4bgh3I6Cyclin-dependent kinase 22.7.11.220.447
1vyzN5BCyclin-dependent kinase 22.7.11.220.446
2w17I19Cyclin-dependent kinase 22.7.11.220.446
1fvv107Cyclin-dependent kinase 22.7.11.220.445
1gii1PUCyclin-dependent kinase 22.7.11.220.445
3ddpRC8Cyclin-dependent kinase 22.7.11.220.445
1hckATPCyclin-dependent kinase 22.7.11.220.444
1oi9N20Cyclin-dependent kinase 22.7.11.220.444
3qqkX02Cyclin-dependent kinase 22.7.11.220.444
1b38ATPCyclin-dependent kinase 22.7.11.220.443
4eon1ROCyclin-dependent kinase 22.7.11.220.443
3qqlX03Cyclin-dependent kinase 22.7.11.220.442
2exmZIPCyclin-dependent kinase 22.7.11.220.441
3py0SU9Cyclin-dependent kinase 22.7.11.220.441
3ral04ZCyclin-dependent kinase 22.7.11.220.440