sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4lwx | MU2 | Ribosome inactivating protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4lwx | MU2 | Ribosome inactivating protein | / | 1.000 | |
| 4jtp | ASC | Ribosome inactivating protein | / | 0.670 | |
| 3qji | MGP | Ribosome inactivating protein | / | 0.604 | |
| 4emr | MGP | Ribosome inactivating protein | / | 0.587 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.576 | |
| 4zz6 | CTP | Ribosome inactivating protein | / | 0.571 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.550 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.508 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.472 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.459 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.458 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.456 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.456 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.452 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.451 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.448 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.446 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.446 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.443 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.440 |