Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4hlh20DTankyrase-22.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4hlh20DTankyrase-22.4.2.301.000
4bueJQFTankyrase-22.4.2.300.763
4l341VGTankyrase-22.4.2.300.756
4l2g1V4Tankyrase-22.4.2.300.733
4l0t1V0Tankyrase-22.4.2.300.696
4l0i1UWTankyrase-22.4.2.300.666
4buuF38Tankyrase-22.4.2.300.659
3kr8XAVTankyrase-22.4.2.300.658
4bu908CTankyrase-22.4.2.300.657
4kzuA73Tankyrase-22.4.2.300.656
4buxF35Tankyrase-22.4.2.300.654
4l10A63Tankyrase-22.4.2.300.654
4hlf15ZTankyrase-22.4.2.300.651
4kzl20DTankyrase-22.4.2.300.644
4buwF33Tankyrase-22.4.2.300.638
4l2f1V3Tankyrase-22.4.2.300.637
4buiW2ETankyrase-22.4.2.300.636
4bufF36Tankyrase-22.4.2.300.635
4l31F08Tankyrase-22.4.2.300.635
4l0s1UZTankyrase-22.4.2.300.633
4but31FTankyrase-22.4.2.300.629
4l0v1V1Tankyrase-22.4.2.300.629
4hkkAGITankyrase-22.4.2.300.627
4l321VFTankyrase-22.4.2.300.619
4iueAJ4Tankyrase-22.4.2.300.614
5aku29FTankyrase-22.4.2.300.614
4hlk431Tankyrase-22.4.2.300.612
4j21AJ6Tankyrase-22.4.2.300.612
4hmhF94Tankyrase-22.4.2.300.611
4hlg20BTankyrase-22.4.2.300.610
4bus32FTankyrase-22.4.2.300.605
4hl515WTankyrase-22.4.2.300.605
4hlm16STankyrase-22.4.2.300.604
4avwG18Tankyrase-22.4.2.300.596
4bud29FTankyrase-22.4.2.300.595
4l33F70Tankyrase-22.4.2.300.594
4hknLU2Tankyrase-22.4.2.300.590
3p0pNNFTankyrase-22.4.2.300.585
4j22AJ7Tankyrase-22.4.2.300.584
4bjbP34Tankyrase-22.4.2.300.577
4pnrG18Tankyrase-22.4.2.300.569
4bs4A64Tankyrase-22.4.2.300.564
4krs1SXTankyrase-12.4.2.300.557
4hkiFLNTankyrase-22.4.2.300.556
4l2k1V8Tankyrase-22.4.2.300.543
4l091URTankyrase-22.4.2.300.538
4msk2C8Tankyrase-12.4.2.300.528
4j3lAJ5Tankyrase-22.4.2.300.517
4j3mAJ8Tankyrase-22.4.2.300.506
4pnmNU1Tankyrase-22.4.2.300.502
4avuLDRTankyrase-22.4.2.300.501
4buv16ITankyrase-22.4.2.300.493
4tjy3GNTankyrase-22.4.2.300.486
1x8lOXRRetinol dehydratase/0.475
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.462
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.462
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.460
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.459
3qm4PN0Cytochrome P450 2D6/0.459
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.455
1kceCB3Thymidylate synthase/0.453
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.448
4li61XOTankyrase-12.4.2.300.446
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.444
1opbRETRetinol-binding protein 2/0.443
1zdwFLVPrenyltransferase/0.443
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2bf7HBIPteridine reductase 11.5.1.330.442
2vqoTFGHistone deacetylase 43.5.1.980.442
4e2yJHZMethyltransferase/0.442
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.441
3ielU5PRibonuclease TTHA02523.10.440
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.440