Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gssGTXGlutathione S-transferase P2.5.1.18

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gssGTXGlutathione S-transferase P2.5.1.181.000
17gsGTXGlutathione S-transferase P2.5.1.180.716
12gs0HHGlutathione S-transferase P2.5.1.180.611
1pgtGTXGlutathione S-transferase P2.5.1.180.599
1gssLEEGlutathione S-transferase P2.5.1.180.557
1guhGSBGlutathione S-transferase A12.5.1.180.506
1nb6UTPGenome polyprotein2.7.7.480.488
3l0hGTXGlutathione S-transferase A12.5.1.180.484
3a5yKAAElongation factor P--(R)-beta-lysine ligase/0.480
3ik9BOBGlutathione S-transferase A12.5.1.180.475
3ktlGTXGlutathione S-transferase A12.5.1.180.475
3zgz84TLeucine--tRNA ligase/0.472
1sesAHXSerine--tRNA ligase6.1.1.110.470
2gvgNMNNicotinamide phosphoribosyltransferase2.4.2.120.468
3q9lATPSeptum site-determining protein MinD/0.467
3enkUPGUDP-glucose 4-epimerase/0.462
2z95NDPGDP-mannose 4,6-dehydratase/0.459
3mx2TTPNucleoprotein/0.459
3qbjNXZDipeptidyl peptidase 4/0.459
2oapANPType II secretion system protein (GspE-2)/0.458
2pz8APCNH(3)-dependent NAD(+) synthetase/0.458
1p4aPCPPur operon repressor/0.457
1z7eATPBifunctional polymyxin resistance protein ArnA/0.457
2a2sGSNGlutathione S-transferase P2.5.1.180.457
2x3jATPAcsD/0.455
2h3dNMNNicotinamide phosphoribosyltransferase2.4.2.120.454
1kqbFMNOxygen-insensitive NAD(P)H nitroreductase/0.453
1pl2ABYGlutathione S-transferase A12.5.1.180.453
2qo7ANPEphrin type-A receptor 32.7.10.10.453
3ulkNDPKetol-acid reductoisomerase (NADP(+))/0.452
1k3lGTXGlutathione S-transferase A12.5.1.180.451
2g89UMPThymidylate synthase/0.451
1kh2ATPArgininosuccinate synthase/0.449
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.449
3wb2YGPUncharacterized protein MJ0488/0.449
4y3jHICEndothiapepsin3.4.23.220.449
1w5bGTPCell division protein FtsZ 1/0.448
5kwvANPPantothenate synthetase/0.448
1p9wANPType II secretion system protein E/0.447
2xclANPPhosphoribosylamine--glycine ligase/0.447
3apwDP0Alpha-1-acid glycoprotein 2/0.447
5djuFMNNPH1-2/0.446
2yy5WSATryptophan--tRNA ligase6.1.1.20.445
3mx5UTPNucleoprotein/0.445
3w8rACPUridine kinase/0.444
2zt5B4PGlycine--tRNA ligase/0.443
3frc0HGGlutathione S-transferase2.5.1.180.443
2yqjUD1UDP-N-acetylglucosamine pyrophosphorylase2.7.7.230.442
3aezGDPPantothenate kinase2.7.1.330.442
4fduIHSPutative multiple inositol polyphosphate histidine phosphatase 1/0.442
4fryNADPutative signal-transduction protein with CBS domains/0.442
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.442
4quvNDPDelta(14)-sterol reductase/0.442
1eu1MGDDimethyl sulfoxide/trimethylamine N-oxide reductase/0.441
2g96NMNNicotinamide phosphoribosyltransferase2.4.2.120.441
3qttANPPantothenate synthetase/0.441
4yqfGDPSeptin-9/0.441
5cwa0GAAnthranilate synthase component 14.1.3.270.441