sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 1.000 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.904 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.848 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.704 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.673 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.667 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.655 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.654 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.629 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.621 | |
| 4ict | 1ED | Mycocyclosin synthase | 1.14.21.9 | 0.609 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.551 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.487 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.482 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.459 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.452 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.446 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.443 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.443 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.441 |