sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 1.000 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.645 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.584 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.557 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.554 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.550 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.495 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.488 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.475 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.472 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.469 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.466 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.461 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.460 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.459 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.459 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.459 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.453 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.452 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.451 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.451 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.450 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.449 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.447 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.446 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.446 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.445 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.445 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.444 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.444 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.442 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.442 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.441 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.441 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 |