Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4c4oNADSADH

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4c4oNADSADH/1.000
2xaaNADSecondary alcohol dehydrogenase/0.536
3jv7NADSecondary alcohol dehydrogenase/0.522
3wleNAD(R)-specific carbonyl reductase/0.522
1ma0NADAlcohol dehydrogenase class-31.1.1.10.490
4dl9NADS-(hydroxymethyl)glutathione dehydrogenase/0.481
1h2bNAJNAD-dependent alcohol dehydrogenase/0.478
4dlbNADS-(hydroxymethyl)glutathione dehydrogenase/0.477
4gl4NAIAlcohol dehydrogenase class-3/0.474
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.473
1adcPADAlcohol dehydrogenase E chain1.1.1.10.472
2oxiNADAlcohol dehydrogenase E chain1.1.1.10.472
2ohxNADAlcohol dehydrogenase E chain1.1.1.10.471
1yqdNAPSinapyl alcohol dehydrogenase/0.467
3ukoNADAlcohol dehydrogenase class-3/0.465
4jjiNADAlcohol dehydrogenase class-3/0.463
4nfhNAJAlcohol dehydrogenase E chain1.1.1.10.460
1cdoNADAlcohol dehydrogenase 11.1.1.10.459
1u3vNADAlcohol dehydrogenase 1B1.1.1.10.457
3twoNDPMannitol dehydrogenase/0.457
1axeNADAlcohol dehydrogenase E chain1.1.1.10.456
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.455
1yqxNAPSinapyl alcohol dehydrogenase/0.454
1a71NADAlcohol dehydrogenase E chain1.1.1.10.452
2jhfNADAlcohol dehydrogenase E chain1.1.1.10.450
1e3lNADAlcohol dehydrogenase 41.1.1.10.449
1hldNADAlcohol dehydrogenase E chain1.1.1.10.447
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.447
4cpdNADAlcohol dehydrogenase/0.444
1agnNADAlcohol dehydrogenase class 4 mu/sigma chain1.1.1.10.443
1ldeNADAlcohol dehydrogenase E chain1.1.1.10.443
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.443
1hszNADAlcohol dehydrogenase 1B1.1.1.10.442
1ht0NADAlcohol dehydrogenase 1C1.1.1.10.442
1adbCNDAlcohol dehydrogenase E chain1.1.1.10.441