scPDB - Distribution of Binding site Similarity values of 3lg5 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3lg5	BTM	Epi-isozizaene synthase	4.2.3.37

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3lg5	BTM	Epi-isozizaene synthase	4.2.3.37	1.000
2rdn	1PL	1-deoxypentalenic acid 11-beta-hydroxylase	1.14.11.35	0.492
2e8u	IPE	Geranylgeranyl pyrophosphate synthase	/	0.490
3zec	ANP	Adenosine monophosphate-protein transferase SoFic	2.7.7.n1	0.489
2rd2	QSI	Glutamine--tRNA ligase	6.1.1.18	0.481
5erm	210	Fusicoccadiene synthase	4.2.3.43	0.475
1nqx	RLP	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.474
1euy	QSI	Glutamine--tRNA ligase	6.1.1.18	0.470
1kyv	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.469
1w19	T2P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.469
1r58	AO5	Methionine aminopeptidase 2	/	0.468
3fr4	F8A	Fatty acid-binding protein, adipocyte	/	0.468
4b65	NDP	L-ornithine N(5)-monooxygenase	/	0.468
3ele	PLP	Aminotransferase	/	0.467
1x2e	ATX	Proline iminopeptidase	3.4.11.5	0.465
1yw7	A41	Methionine aminopeptidase 2	/	0.464
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.463
3pkd	Y10	Methionine aminopeptidase 2	/	0.461
4dyn	0MR	Nucleoprotein	/	0.461
1dgf	NDP	Catalase	1.11.1.6	0.460
2qw8	NAP	Eugenol synthase 1	1.1.1.318	0.460
4dya	0MF	Nucleoprotein	/	0.459
1yw9	A84	Methionine aminopeptidase 2	/	0.458
2idv	M7G	Eukaryotic translation initiation factor 4E-1	/	0.457
3elb	C5P	Ethanolamine-phosphate cytidylyltransferase	2.7.7.14	0.457
1qip	GNB	Lactoylglutathione lyase	4.4.1.5	0.456
2qt0	NNR	Nicotinamide riboside kinase 1	/	0.456
4tnz	TTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.456
1gtr	ATP	Glutamine--tRNA ligase	6.1.1.18	0.455
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.455
2q94	A04	Methionine aminopeptidase	/	0.454
4jxx	ATP	Glutamine--tRNA ligase	6.1.1.18	0.454
5kf2	ACO	Predicted acetyltransferase	/	0.454
1nqw	5YL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.453
2q92	B23	Methionine aminopeptidase	/	0.452
2xej	OKD	Glutamate carboxypeptidase 2	3.4.17.21	0.452
2z4w	749	Geranylgeranyl pyrophosphate synthase	/	0.452
1qru	ATP	Glutamine--tRNA ligase	6.1.1.18	0.451
3c49	KU8	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.451
4dyp	0MS	Nucleoprotein	/	0.451
1y2b	DEE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.450
4i6h	1C8	Serine/threonine-protein kinase PLK2	2.7.11.21	0.450
4j7h	TRH	PCZA361.3	/	0.450
1gti	GTB	Glutathione S-transferase P 1	2.5.1.18	0.449
2geu	COK	Pantothenate kinase	2.7.1.33	0.449
2r86	ATP	5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase	/	0.449
2wq7	FAD	RE11660p	/	0.449
2zsb	ADP	Pantothenate kinase	2.7.1.33	0.449
1tou	B1V	Fatty acid-binding protein, adipocyte	/	0.448
2rds	1PL	1-deoxypentalenic acid 11-beta-hydroxylase	1.14.11.35	0.448
1udt	VIA	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.447
4c1i	EH9	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.447
4hcy	0YN	Transketolase	/	0.447
2ea4	F79	Methionine aminopeptidase 2	/	0.446
3ceh	AVE	Glycogen phosphorylase, liver form	2.4.1.1	0.446
1vhn	FMN	tRNA-dihydrouridine synthase	/	0.445
1zis	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.445
2d2g	DZZ	Phosphotriesterase	/	0.445
2ouu	35G	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.445
2xb8	XNW	3-dehydroquinate dehydratase	4.2.1.10	0.445
3af1	GDP	Pantothenate kinase	2.7.1.33	0.445
4jyz	ATP	Glutamine--tRNA ligase	6.1.1.18	0.445
5kf9	ACO	Predicted acetyltransferase	/	0.445
1mmv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.444
1x2b	STX	Proline iminopeptidase	3.4.11.5	0.444
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.444
2gev	COK	Pantothenate kinase	2.7.1.33	0.444
1vot	HUP	Acetylcholinesterase	3.1.1.7	0.443
4ba5	PXG	Probable aminotransferase	/	0.443
5liu	388	Aldo-keto reductase family 1 member B10	1.1.1	0.443
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.442
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.442
2gg0	U11	Methionine aminopeptidase	/	0.442
4h9t	HL4	Phosphotriesterase	/	0.442
4llk	MEW	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.442
2q93	B21	Methionine aminopeptidase	/	0.441
3jsi	WTC	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.441
3ryk	TYD	dTDP-4-dehydrorhamnose 3,5-epimerase	/	0.441
3uyk	0CX	Probable NDP-rhamnosyltransferase	/	0.441
5d0r	B1T	Adenylate cyclase type 10	/	0.441
1p0p	BCH	Cholinesterase	3.1.1.8	0.440
1z5u	CMP	Class B acid phosphatase	/	0.440
2r1n	EPL	Phosphotriesterase	/	0.440
3c1o	NAP	Eugenol synthase	/	0.440
4jsr	1NQ	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	3.5.1	0.440
5kf8	ACO	Predicted acetyltransferase	/	0.440