Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3cokANPSerine/threonine-protein kinase PLK42.7.11.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3cokANPSerine/threonine-protein kinase PLK42.7.11.211.000
4c3pACPAurora kinase A2.7.11.10.528
2qoqANPEphrin type-A receptor 32.7.10.10.508
4qmlANPSerine/threonine-protein kinase 242.7.11.10.503
2c6eHPMAurora kinase A2.7.11.10.501
4jboWPHAurora kinase A2.7.11.10.499
4o0uADNAurora kinase A2.7.11.10.496
1mqbANPEphrin type-A receptor 22.7.10.10.491
2wqeADPAurora kinase A2.7.11.10.491
2ijmATPFocal adhesion kinase 12.7.10.20.490
2j0lANPFocal adhesion kinase 12.7.10.20.490
1i44ACPInsulin receptor2.7.10.10.487
4jbpYPHAurora kinase A2.7.11.10.487
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.486
4j99ACPFibroblast growth factor receptor 2/0.483
2henADPEphrin type-B receptor 22.7.10.10.481
3c4xATPRhodopsin kinase/0.480
5l8lADPAurora kinase A2.7.11.10.478
2qo7ANPEphrin type-A receptor 32.7.10.10.477
3c4wATPRhodopsin kinase/0.477
3c4zADPRhodopsin kinase/0.463
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.461
3t8oATPRhodopsin kinase/0.461
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
3a7hATPSerine/threonine-protein kinase 242.7.11.10.460
3begANPSRSF protein kinase 12.7.11.10.459
4l9i8PRRhodopsin kinase/0.458
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.456
4xlvACPInsulin receptor2.7.10.10.456
5dnrATPAurora kinase A2.7.11.10.456
2j7t274Serine/threonine-protein kinase 102.7.11.10.455
2qocANPEphrin type-A receptor 32.7.10.10.454
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.451
5av3KMPDeath-associated protein kinase 12.7.11.10.451
2vrx447Aurora kinase B-A2.7.11.10.450
4ysjADPCalmodulin-like domain protein kinase/0.450
3zxtACPDeath-associated protein kinase 12.7.11.10.449
4qnyANPMitogen activated protein kinase, putative/0.449
2cjmATPCyclin-dependent kinase 22.7.11.220.448
5eg3ACPFibroblast growth factor receptor 2/0.448
2v7a627Tyrosine-protein kinase ABL12.7.10.20.446
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.446
2ojj82AMitogen-activated protein kinase 12.7.11.240.445
2ijmADPFocal adhesion kinase 12.7.10.20.444
2vwu7X1Ephrin type-B receptor 42.7.10.10.443
4deeADPAurora kinase A2.7.11.10.443
3d7tSTUTyrosine-protein kinase CSK/0.442
4i3zADPCyclin-dependent kinase 22.7.11.220.442
5av2KMPDeath-associated protein kinase 12.7.11.10.441
3qc9ADPRhodopsin kinase/0.440