sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2jlb | UDM | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2jlb | UDM | Uncharacterized protein | / | 1.000 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.470 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.463 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.458 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.458 | |
| 4k97 | ATP | Cyclic GMP-AMP synthase | / | 0.458 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.455 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.453 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.452 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.451 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.451 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.451 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.450 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.449 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.449 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.448 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.447 | |
| 5cns | CDP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.447 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.446 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.445 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 4ohx | ADP | Protein clpf-1 | / | 0.444 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.443 | |
| 1lrl | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.442 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.442 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.442 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.441 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.441 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3vgl | ANP | Glucokinase | / | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.440 | |
| 4l9q | 9TP | Serum albumin | / | 0.440 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.440 | |
| 4xsv | CTP | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 |