Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1zw5ZOLFarnesyl pyrophosphate synthase2.5.1.10

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1zw5ZOLFarnesyl pyrophosphate synthase2.5.1.101.000
3ryeUNRFarnesyl pyrophosphate synthase2.5.1.100.623
3ez3ZOLFarnesyl pyrophosphate synthase, putative/0.617
4dwb0M7Farnesyl pyrophosphate synthase/0.610
3dyh721Farnesyl pyrophosphate synthase/0.607
3ldwZOLFarnesyl pyrophosphate synthase, putative/0.605
4kqsRISFarnesyl pyrophosphate synthase2.5.1.100.603
3rbmB73Farnesyl pyrophosphate synthase, putative/0.592
3rywK9HFarnesyl pyrophosphate synthase, putative/0.590
2opmNI9Farnesyl pyrophosphate synthase2.5.1.100.588
2f94BFQFarnesyl pyrophosphate synthase2.5.1.100.587
4lfvYS4Farnesyl pyrophosphate synthase2.5.1.100.580
4q23RISFarnesyl pyrophosphate synthase2.5.1.100.579
4kqsIPEFarnesyl pyrophosphate synthase2.5.1.100.577
4nkeRISFarnesyl pyrophosphate synthase2.5.1.100.574
3ldwIPEFarnesyl pyrophosphate synthase, putative/0.563
3egt722Farnesyl pyrophosphate synthase/0.562
2i191BYFarnesyl pyrophosphate synthase/0.554
4dxj0M9Farnesyl pyrophosphate synthase/0.551
4nkeIPEFarnesyl pyrophosphate synthase2.5.1.100.548
4lfgIPEPutative geranyltranstransferase/0.541
3krfDSTGeranyl diphosphate synthase large subunit/0.540
1rqjRISFarnesyl diphosphate synthase2.5.1.100.539
3ez3IPEFarnesyl pyrophosphate synthase, putative/0.537
1yq7RISFarnesyl pyrophosphate synthase2.5.1.100.535
3oabDSTGeranyl diphosphate synthase large subunit/0.528
1yv5RISFarnesyl pyrophosphate synthase2.5.1.100.522
3krfIPEGeranyl diphosphate synthase large subunit/0.519
1rqjIPEFarnesyl diphosphate synthase2.5.1.100.518
2o1oRISPutative farnesyl pyrophosphate synthase/0.497
2opnSUFFarnesyl pyrophosphate synthase2.5.1.100.493
5ero210Fusicoccadiene synthase2.5.1.290.493
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.468
4k10NI9Farnesyl pyrophosphate synthase/0.467
2e91ZOLGeranylgeranyl pyrophosphate synthase/0.458
2e8wIPEGeranylgeranyl pyrophosphate synthase/0.457
3iczPB6Farnesyl pyrophosphate synthase/0.452
1dliUDXUDP-glucose 6-dehydrogenase/0.451
2gvdGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.447
2wvmGDDMannosyl-3-phosphogylcerate synthase/0.447
4ga34GAFarnesyl pyrophosphate synthase2.5.1.100.447
4mvcCDCCholine-phosphate cytidylyltransferase A/0.447
5agaANPDNA polymerase theta/0.447
5ayzNCNNicotinate-nucleotide pyrophosphorylase [carboxylating]2.4.2.190.444
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.443
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.443
4e07ACPPlasmid partitioning protein ParF/0.443
5a65TPPThiamine-triphosphatase3.6.1.280.442
4jvj1MVFarnesyl pyrophosphate synthase2.5.1.100.441
2hs0ATPPhosphoribosylformylglycinamidine synthase subunit PurL/0.440