sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.864 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.860 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.828 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.790 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.788 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.717 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.680 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.678 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.678 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.669 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.649 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.644 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.642 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.642 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.640 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.637 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.637 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.632 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.631 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.629 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.627 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.626 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.625 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.621 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.621 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.620 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.615 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.609 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.606 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.603 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.603 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.603 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.602 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.599 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.598 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.594 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.590 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.587 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.585 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.584 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.582 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.579 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.578 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.576 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.575 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.575 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.564 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.558 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.554 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.540 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.540 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.521 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.511 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.505 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.502 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.497 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.495 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.494 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.493 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.491 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.490 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.483 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.479 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.475 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.472 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.470 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.469 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.467 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.467 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.465 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.460 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.457 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.457 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.457 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.456 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.455 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.453 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.450 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.450 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.450 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.450 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.448 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.447 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.447 | |
| 2y3s | TIR | TamL | / | 0.446 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.445 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.445 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.445 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.444 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.443 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 |