scPDB - Distribution of Binding site Similarity values of 1id0 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1id0	ANP	Sensor protein PhoQ	2.7.13.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1id0	ANP	Sensor protein PhoQ	2.7.13.3	1.000
4bix	ADP	Sensor histidine kinase CpxA	/	0.501
2o1x	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.490
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.488
3f63	GTX	Glutathione transferase GST1-4	/	0.479
2c2a	ADP	Sensor histidine kinase	/	0.477
1i58	ACP	Chemotaxis protein CheA	2.7.13.3	0.476
2ix5	FAD	Acyl-coenzyme A oxidase 4, peroxisomal	1.3.3.6	0.474
4cav	MYA	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.473
2oap	ANP	Type II secretion system protein (GspE-2)	/	0.471
1i59	ANP	Chemotaxis protein CheA	2.7.13.3	0.467
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.467
4ohw	ATP	Protein clpf-1	/	0.467
3sl2	ATP	Sensor histidine kinase WalK	/	0.465
4nmd	FDA	Bifunctional protein PutA	/	0.465
4u9y	COA	Alpha-tubulin N-acetyltransferase 1	/	0.465
2trt	TAC	Tetracycline repressor protein class D	/	0.463
2pg0	FAD	Acyl-CoA dehydrogenase	/	0.462
4cjx	9L9	C-1-tetrahydrofolate synthase, cytoplasmic, putative	/	0.462
1i59	ADP	Chemotaxis protein CheA	2.7.13.3	0.459
1r6u	TYM	Tryptophan--tRNA ligase, cytoplasmic	6.1.1.2	0.459
4fxf	ATP	Pyruvate kinase PKM	2.7.1.40	0.459
2pui	ADP	Methylthioribose kinase	2.7.1.100	0.458
3zkp	ERB	Erythromycin C-12 hydroxylase	1.14.13.154	0.458
2xpw	OTC	Tetracycline repressor protein class D	/	0.457
3fhy	ATP	Pyridoxal kinase	2.7.1.35	0.457
1qiq	ACC	Isopenicillin N synthase	1.21.3.1	0.456
1qlh	NAD	Alcohol dehydrogenase E chain	1.1.1.1	0.455
4xgu	ADP	Putative pachytene checkpoint protein 2	/	0.455
3vwe	COA	Alpha-tubulin N-acetyltransferase 1	/	0.454
1r8q	AFB	Cytohesin-2	/	0.453
1r8q	AFB	ADP-ribosylation factor 1	/	0.453
2chx	090	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.453
3v0p	4GW	Histo-blood group ABO system transferase	/	0.453
4cax	MYA	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.453
4gl4	NAI	Alcohol dehydrogenase class-3	/	0.453
1ej2	NAD	Nicotinamide-nucleotide adenylyltransferase	2.7.7.1	0.452
1i5a	ACP	Chemotaxis protein CheA	2.7.13.3	0.452
2x7h	PFN	Prostaglandin reductase 3	1	0.452
3m9v	TYD	FAD-dependent oxidoreductase	/	0.452
4h1m	0YJ	Protein-tyrosine kinase 2-beta	2.7.10.2	0.452
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.451
2a4n	COA	Aac(6')-Ii protein	/	0.451
2b4r	AES	Glyceraldehyde-3-phosphate dehydrogenase	/	0.451
2bu2	ATP	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	2.7.11.2	0.451
2qc8	ADP	Glutamine synthetase	6.3.1.2	0.451
3crl	ANP	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	2.7.11.2	0.451
4cvm	ANP	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	/	0.451
4q71	FAD	Bifunctional protein PutA	/	0.451
2ga9	AGS	Poly(A) polymerase catalytic subunit	2.7.7.19	0.450
2ivi	ACW	Isopenicillin N synthase	1.21.3.1	0.450
2lfo	GCH	Fatty acid-binding protein, liver	/	0.450
2p9c	NAI	D-3-phosphoglycerate dehydrogenase	1.1.1.95	0.450
1g93	UPG	N-acetyllactosaminide alpha-1,3-galactosyltransferase	/	0.449
1i5b	ANP	Chemotaxis protein CheA	2.7.13.3	0.449
1nhh	ANP	DNA mismatch repair protein MutL	/	0.449
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.449
4gdy	0X1	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.449
2q4b	NAP	Uncharacterized protein At5g02240	/	0.448
2vn1	FK5	Peptidylprolyl isomerase	/	0.448
2xgs	44P	Uncharacterized protein	/	0.448
2yxu	ATP	Pyridoxal kinase	2.7.1.35	0.448
2zat	NAP	Dehydrogenase/reductase SDR family member 4	1.1.1.184	0.448
3f3s	NAD	Lambda-crystallin homolog	/	0.448
3uk6	ADP	RuvB-like 2	3.6.4.12	0.448
3v9v	21L	Peroxisome proliferator-activated receptor gamma	/	0.448
4f4d	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.448
4pl9	ADP	Ethylene receptor 1	/	0.448
5hwo	HMG	Hydroxymethylglutaryl-CoA synthase	/	0.448
2ok7	FAD	Ferredoxin--NADP reductase, apicoplast	/	0.447
4biw	ANP	Sensor histidine kinase CpxA	/	0.447
2rgo	FAD	Alpha-Glycerophosphate Oxidase	/	0.446
2vn0	TDZ	Cytochrome P450 2C8	/	0.446
3jsw	JAR	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.446
4g9k	FAD	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9	0.446
1hb3	SCV	Isopenicillin N synthase	1.21.3.1	0.445
3dyl	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.445
3fow	IMH	Purine nucleoside phosphorylase	/	0.445
3rq8	AP5	ADP-dependent (S)-NAD(P)H-hydrate dehydratase	/	0.445
4biz	ADP	Sensor histidine kinase CpxA	/	0.445
4jji	NAD	Alcohol dehydrogenase class-3	/	0.445
5ab7	MLC	Nonspecific lipid-transfer protein, putative	/	0.445
5c6c	CMP	cGMP-dependent protein kinase 2	2.7.11.12	0.445
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.444
2r8o	T5X	Transketolase 1	/	0.444
3zvm	ADP	Bifunctional polynucleotide phosphatase/kinase	2.7.1.78	0.444
4o8a	FAD	Bifunctional protein PutA	1.2.1.88	0.444
1cf3	FAD	Glucose oxidase	1.1.3.4	0.443
1x8v	ESL	Lanosterol 14-alpha demethylase	1.14.13.70	0.443
2y0m	ACO	Histone acetyltransferase KAT8	/	0.443
3keu	ATP	Pyridoxal kinase	2.7.1.35	0.443
3qv1	NAD	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic	1.2.1.13	0.443
4bge	PYW	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.443
1al7	HST	Peroxisomal (S)-2-hydroxy-acid oxidase	1.1.3.15	0.442
1eio	GCH	Gastrotropin	/	0.442
1gjv	AGS	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial	2.7.11.4	0.442
1i5c	ADP	Chemotaxis protein CheA	2.7.13.3	0.442
1kqu	BR4	Phospholipase A2, membrane associated	/	0.442
2qd4	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.442
2x9d	ITC	Tetracycline repressor protein class D	/	0.442
3qaa	G04	Gag-Pol polyprotein	3.4.23.16	0.442
5ecc	NAP	Dehydrofolate reductase type I	/	0.442
1a5u	ATP	Pyruvate kinase PKM	2.7.1.40	0.441
2r8p	T6F	Transketolase 1	/	0.441
3a1c	ACP	Probable copper-exporting P-type ATPase A	3.6.3.54	0.441
3t99	ADP	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2	/	0.441
4d7m	TDC	Tetracycline repressor protein class D	/	0.441
4e2y	JHZ	Methyltransferase	/	0.441
4rvu	NDP	Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)	/	0.441
2xb5	I7T	Tetracycline repressor protein class D	/	0.440
2xsz	ATP	RuvB-like 2	3.6.4.12	0.440
3nx4	NAP	Putative oxidoreductase	/	0.440
3v0o	4GW	Histo-blood group ABO system transferase	/	0.440
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.440
4u07	ATP	Adenosine monophosphate-protein transferase FICD	2.7.7.n1	0.440
5iqi	GNP	Bifunctional AAC/APH	2.3.1	0.440